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Paper Details

Adaptive Evolution of the GDH2 Allosteric Domain Promotes Gliomagenesis by Resolving IDH1-Induced Metabolic Liabilities.
Cancer Research
28
2018
D-(2)-hydroxyglutarate, D2HG, GDH2, GDH2 Allosteric Domain, GDH2 allosteric domain, Gliomagenesis, IDH, IDH mutations, IDH1, IDH1 mutations, IDH1R132H, actively proliferating tumor cells, amino acid, cancers, dipeptide, glioma, gliomagenic neural progenitor cells, gliomas, glutamate, glutamate dehydrogenase, human, isocitrate, isocitrate dehydrogenase 1, isocitrate dehydrogenase 1 (IDH1) gene, malignant gliomas, mouse, murine, tricarboxylic acid, tumor
Author NameAffiliation
Roger E McLendonDuke University
Roger E McLendonDuke University Medical Center
Henry S FriedmanDuke University Medical Center
Henry S FriedmanDuke University Medical Center
Yiping HeDuke University
Yiping HeDuke University Medical Center
Darell D BignerDuke University Medical Center
Darell D BignerDuke University Medical Center
Hai YanDuke University
Hai YanDuke University Medical Center
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