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Paper Details

A BRCA1 Coiled-Coil Domain Variant Disrupting PALB2 Interaction Promotes the Development of Mammary Tumors and Confers a Targetable Defect in Homologous Recombination Repair.
Cancer Res
7
2021
BRCA1, BRCA1 coiled-coil domain, BRCA1 missense variant, BRCA1 tumor suppressor gene, BRCA2, BRCT, Brca1, Brca1 p, Brca1 p., Brca1 p.L1363P, DNA, DNA double-strand breaks, L1363P, PALB2, PARP, RING, Trp53, Trp53-, Trp53-deficient mammary tumors, breast cancer, cisplatin, embryonic lethality, hereditary breast cancer, mammary tumors, mice, p, p.L1363P, tumors
Author NameAffiliation
Colin C PritchardMouse Clinic for Cancer and Aging (MCCA), The Netherlands Cancer Institute
Bing XiaRutgers Cancer Institute of New Jersey
Bing XiaRutgers Cancer Institute of New Jersey
Haico van AttikumLeiden University Medical Center
Jos JonkersOncode Institute and Division of Molecular Pathology, The Netherlands Cancer Institute
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