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Paper Details

A novel anti-inflammatory role links the CARS2 locus to protection from coronary artery disease.
Atherosclerosis
3
2022
13.q34, CAD, CAD risk allele, CARKD, CARS2, CARS2 gene, CARS2 locus, CARS2 siRNA, CARS2 silenced macrophages, G, GWAS-identified variant, IL-10, IL10, ING1, LPS-induced genes, M1, M2 macrophages, SMC, SMCs, STAT3, THP-1 derived macrophages, THP-1 monocytes, anti-inflammatory (M2) macrophages, co, contractile genes, coronary artery disease, human, human macrophages, inflammatory genes, intergenic region, macrophages, proinflammatory (M1), rs61969072, smooth muscle cells
Author NameAffiliation
Ruth McPhersonUniversity of Ottawa Heart Institute
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