Paper Details

Paper Title

Chemogenetic profiling identifies RAD17 as synthetically lethal with checkpoint kinase inhibition.

Paper Journal Title

Oncotarget

Paper Citation Count

Paper Publication Year

2015

Bio Mention

CHEK1, CHEK1/, CHEK1/2, CHEK1/2 mutant cell, CHEK2, CHEK2 checkpoint kinases, H2AX, RAD17, RAD17 knockdown cell lines, RAD17 wild-, Replication Factor C, Saccharomyces cerevisiae, WEE1, cancer, cancer cell lines, checkpoint, checkpoint kinase, checkpoint kinases, patients, tumor, tumor suppressor genes, tumors, yeast

Mesh Descriptor

Antineoplastic Agents, Biomarkers, Pharmacological, Cell Cycle, Cell Cycle Proteins, Checkpoint Kinase 1, Checkpoint Kinase 2, DNA Damage, DNA-Binding Proteins, Drug Discovery, HeLa Cells, Humans, Molecular Targeted Therapy, Mutation, Neoplasms, Nuclear Proteins, Protein Kinases, Protein-Tyrosine Kinases, RNA, Small Interfering, Saccharomyces cerevisiae, Saccharomyces cerevisiae Proteins, Thiophenes, Urea

Author Name	Affiliation
John Paul Shen	University of California San Diego
John Paul Shen	Moores Cancer Center, University of California San Diego
Rohith Srivas	University of California San Diego
Rohith Srivas	Stanford University School of Medicine
Andrew M Gross	University of California San Diego
Jianfeng Li	University of Pittsburgh School of Medicine
Jianfeng Li	University of Pittsburgh Cancer Institute, Hillman Cancer Center
Jianfeng Li	University of South Alabama Mitchell Cancer Institute
Eric J Jaehnig	University of California San Diego
Eric J Jaehnig	Ludwig Institute for Cancer Research, University of California San Diego
Eric J Jaehnig	University of California San Diego
Eric J Jaehnig	Ludwig Institute for Cancer Research, University of California San Diego
Su Ming Sun	Leiden University Medical Center
Ana Bojorquez-Gomez	University of California San Diego
Katherine Licon	University of California San Diego
Vignesh Sivaganesh	University of California San Diego
Jia L Xu	University of California San Diego
Kristin Klepper	University of California San Diego
Huwate Yeerna	University of California San Diego
Daniel Pekin	University of California San Diego
Chu Ping Qiu	University of California San Diego
Haico van Attikum	Leiden University Medical Center
Robert W Sobol	University of Pittsburgh School of Medicine
Robert W Sobol	University of Pittsburgh Cancer Institute, Hillman Cancer Center
Robert W Sobol	University of South Alabama Mitchell Cancer Institute
Trey Ideker (CM4AI)	University of California San Diego
Trey Ideker (CM4AI)	Moores Cancer Center, University of California San Diego
Trey Ideker (CM4AI)	University of California San Diego
Trey Ideker (CM4AI)	University of California San Diego
Trey Ideker (CM4AI)	Moores Cancer Center, University of California San Diego
Trey Ideker (CM4AI)	University of California San Diego

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