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Paper Details

DCZ0415, a small-molecule inhibitor targeting TRIP13, inhibits EMT and metastasis via inactivation of the FGFR4/STAT3 axis and the Wnt/β-catenin pathway in colorectal cancer.
Mol Oncol
11
2022
AAA-ATPase family, BRAF, CRC, CRC cells, CRCs, CTLA4, DCZ04145, DCZ0415, FGFR4, KRAS, NF-?, PD1, STAT3, T-cell factor 1, TRIP13, TRIP13-deregulated cancer cell lines, Thyroid receptor-interacting protein 13, Wnt, cancer, cancers, cells, colorectal cancer, cyclin D1, epidermal growth factor receptor, epithelial, fibroblast growth factor receptor 4, granzyme B, human, interferon gamma, mice, nuclear factor kappa B, p53, perforin, signal transducer and activator of transcription 3, tumour
Author NameAffiliation
Farrukh AfaqUniversity of Alabama at Birmingham
Sooryanarayana VaramballyUniversity of Alabama at Birmingham
Sooryanarayana VaramballyO'Neal Comprehensive Cancer Center, University of Alabama at Birmingham
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