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Paper Details

SIRT5 is a proviral factor that interacts with SARS-CoV-2 Nsp14 protein.
PLoS Pathog
17
2022
MAVS, Mitochondrial Antiviral Signaling Protein, N7-methyltransferase, NAD, NAD-dependent protein deacylase, Nsp10, Nsp14, SARS, SARS-CoV-2, SARS-CoV-2 Nsp14 protein, SARS-CoV-2 non-structural protein Nsp14, SIRT5, SIRT5 catalytic domain, SIRT5 knock-out cells, cell, cell-culture, human, human sirtuin 5, knock-out cells, lysine, malonyl, succinyl
Antiviral Agents, COVID-19, Exoribonucleases, Humans, Lysine, Methyltransferases, NAD, Proviruses, RNA, Viral, SARS-CoV-2, Sirtuins, Viral Nonstructural Proteins
Author NameAffiliation
Marius WalterBuck Institute for Research on Aging
Irene P ChenGladstone Institutes
Irene P ChenUniversity of California San Francisco
Irene P Chen
Albert Vallejo-GraciaGladstone Institutes
Albert Vallejo-GraciaUniversity of California San Francisco
Albert Vallejo-Gracia
Ik-Jung KimBuck Institute for Research on Aging
Olga BielskaBuck Institute for Research on Aging
Victor L LamUniversity of California San Francisco
Jennifer M HayashiGladstone Institutes
Jennifer M HayashiUniversity of California San Francisco
Jennifer M Hayashi
Andrew CruzBuck Institute for Research on Aging
Samah ShahBuck Institute for Research on Aging
Frank W SovegGladstone Institutes
Frank W SovegUniversity of California San Francisco
Frank W Soveg
John D GrossUniversity of California San Francisco
John D GrossQuantitative Biosciences Institute (QBI), University of California San Francisco
Nevan J Krogan (CM4AI)Gladstone Institutes
Nevan J Krogan (CM4AI)University of California San Francisco
Nevan J Krogan (CM4AI)
Nevan J Krogan (CM4AI)Quantitative Biosciences Institute (QBI), University of California San Francisco
Keith R JeromeFred Hutch Cancer Center
Keith R JeromeUniversity of Washington
Birgit SchillingBuck Institute for Research on Aging
Birgit SchillingBuck Institute for Research on Aging
Melanie OttGladstone Institutes
Melanie OttUniversity of California San Francisco
Melanie Ott
Melanie Ott
Eric VerdinBuck Institute for Research on Aging
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