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Paper Details

Induction of anaplastic lymphoma kinase (ALK) as a novel mechanism of EGFR inhibitor resistance in head and neck squamous cell carcinoma patient-derived models.
Cancer Biol Ther
10
2018
3D, ALK, ALK fusions, EGFR, HNSCC, HNSCC cell, HNSCC cells, Head and neck squamous cell carcinoma, anaplastic lymphoma, anaplastic lymphoma kinase, brigatinib, cancer, ceritinib, cetuximab, epidermal growth factor receptor, gefitinib, head and neck squamous cell carcinoma, head and neck squamous cell carcinoma patient-derived models, lung cancer, mice, patient, patient-derived cell culture models, patients, siRNA, tumor, tumor cells, tumors
Anaplastic Lymphoma Kinase, Animals, Antineoplastic Agents, Cell Line, Tumor, Disease Models, Animal, Drug Resistance, Neoplasm, ErbB Receptors, Gene Expression Regulation, Neoplastic, Humans, Mice, Phosphorylation, Protein Kinase Inhibitors, RNA Interference, RNA, Small Interfering, Squamous Cell Carcinoma of Head and Neck, Xenograft Model Antitumor Assays
Author NameAffiliation
Xiaoming OuyangOregon Health & Science University
Xiaoming OuyangOregon Health & Science University
Ashley BarlingOregon Health & Science University
Aletha LeschOregon Health & Science University
Jeffrey W TynerOregon Health & Science University
Jeffrey W TynerOregon Health & Science University
Jeffrey W Tynere Knight Cancer Institute, Oregon Health & Science University
Gabrielle ChoonooDepartment of Medical Informatics & Clinical Epidemiology , Oregon Health & Science University
Christina L ZhengDepartment of Medical Informatics & Clinical Epidemiology , Oregon Health & Science University
Sophia JengDepartment of Medical Informatics & Clinical Epidemiology , Oregon Health & Science University
Toni M WestUniversity of California at Davis
Daniel R ClayburghOregon Health & Science University
Daniel R Clayburgh0 SW US Veterans Hospital Rd.
Sara A CourtneidgeOregon Health & Science University
Sara A Courtneidgee Knight Cancer Institute, Oregon Health & Science University
Shannon K McWeeneyDepartment of Medical Informatics & Clinical Epidemiology , Oregon Health & Science University
Molly Kulesz-MartinOregon Health & Science University
Molly Kulesz-MartinOregon Health & Science University
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