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Paper Details

Germline TP53 mutations undergo copy number gain years prior to tumor diagnosis.
Nat Commun
9
2023
AKT, Germline, LFS, LFS tumors, Li-Fraumeni syndrome, PI3K, TP53, TP53 mutations, TP53 pathogenic variants, Wnt, epigenetic modifiers, hereditary cancer predisposition syndrome, homologous recombination genes, mutant TP53, mutant allele, patients, tumor, tumors
Author NameAffiliation
Richard de BorjaThe Hospital for Sick Children
Jonathan L FinlayThe Ohio State University College of Medicine
Moritz GerstungEuropean Bioinformatics Institute EMBL-EBI
Moritz GerstungGerman Cancer Research Centre DKFZ
Ludmil B AlexandrovDepartment of Bioengineering and Moores Cancer Center, University of California
Ludmil B AlexandrovDepartment of Bioengineering and Moores Cancer Center, University of California
David MalkinThe Hospital for Sick Children
David MalkinUniversity of Toronto
David MalkinThe Hospital for Sick Children
David MalkinUniversity of Toronto
David MalkinThe Hospital for Sick Children
David MalkinUniversity of Toronto
David MalkinThe Hospital for Sick Children
David MalkinUniversity of Toronto
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