Skip to Main Content

Paper Details

Discovery and characterization of targetable NTRK point mutations in hematologic neoplasms.
Blood
19
2020
NTRK, NTRK point mutations, NTRK2, NTRK2A203T, NTRK2R458G, NTRK3, NTRK3E176D, NTRK3L449F, Trk, Trk fusions, TrkB, activating, cancer, entrectinib, hematologic neoplasms, hematological malignancies, larotrectinib, leukemias, leukemogenesis, neurotrophic receptor tyrosine kinase, neurotrophic receptor tyrosine kinase (NTRK) genes, patients, pediatric, solid tumors, tumor
Animals, Base Sequence, Benzamides, Cell Line, Drug Resistance, Neoplasm, Hematologic Neoplasms, Humans, Indazoles, Lipid Metabolism, Membrane Glycoproteins, Mice, Mutant Proteins, Oncogenes, Point Mutation, Protein Kinase Inhibitors, Protein Multimerization, RNA, Small Interfering, Receptor, trkB, Receptor, trkC, Recombinant Proteins
Author NameAffiliation
Sunil K JoshiKnight Cancer Institute.
Sunil K JoshiOregon Health & Science University
Sunil K Joshi
Kristin QianKnight Cancer Institute.
William H BissonKnight Cancer Institute.
William H BissonOregon State University
Kevin Watanabe-SmithKnight Cancer Institute.
Ariane HuangKnight Cancer Institute.
Daniel BottomlyKnight Cancer Institute.
Elie TraerKnight Cancer Institute.
Elie Traer
Elie TraerOregon Health & Science University
Jeffrey W TynerKnight Cancer Institute.
Jeffrey W Tyner
Jeffrey W TynerOregon Health & Science University
Shannon K McWeeneyDepartment of Medical Informatics and Clinical Epidemiology.
Shannon K McWeeneyKnight Cancer Institute.
Monika A Davare
Monika A Davare
Monika A DavarePape Pediatric Research Institute.
Monika A Davare
Monika A DavarePape Pediatric Research Institute.
Monika A Davare
Brian J DrukerKnight Cancer Institute.
Brian J DrukerOregon Health & Science University
Brian J Druker
Brian J DrukerHoward Hughes Medical Institute, Oregon Health & Science University
Cristina E TognonKnight Cancer Institute.
Cristina E TognonOregon Health & Science University
Cristina E TognonHoward Hughes Medical Institute, Oregon Health & Science University
  • 1 - 30

Datasets

Release 1.2