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Paper Details

Cooperative Epigenetic Remodeling by TET2 Loss and NRAS Mutation Drives Myeloid Transformation and MEK Inhibitor Sensitivity.
Cancer Cell
66
2018
CMML, MAPK, MAPK kinase, MEK, NRAS, NRAS mutations, Nras, Nras double-mutant leukemia, NrasG12D, Spry2, TET2, Tet2, chronic myelomonocytic leukemia, genetic lesions, hematopoietic cells, mitogen-activated protein kinase, mouse, myeloid, myeloid malignancies, patient, patients
Author NameAffiliation
Cem MeydanInstitute for Computational Biomedicine and Department of Physiology and Biophysics, Weill Cornell Medical College
Francine E Garrett-BakelmanWeill Cornell Medical College, University of Virginia
Francine E Garrett-BakelmanWeill Cornell Medical College, University of Virginia
Martin S TallmanMemorial Sloan Kettering Cancer Center
Ari MelnickWeill Cornell Medical College
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