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The selenium-containing drug ebselen potently disrupts LEDGF/p75-HIV-1 integrase interaction by targeting LEDGF/p75.
Journal of Enzyme Inhibition and Medicinal Chemistry
14
2020
2-phenyl-1,2-benzisoselenazol-3-one, DTT, Ebselen, HIV-, HIV-1, HIV-1 integrase, IN, LEDGF, LEDGF-IN, LEDGINs, Lens-epithelium-derived growth-factor, Lens-epithelium-derived growth-factor (LEDGF/p75)-binding site, dithiothreitol, ebselen, p75, p75-IN, selenium, sulphur, thiols
Author NameAffiliation
Shan ChangJiangsu University of Technology
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