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Paper Details

Somatic driver mutation prevalence in 1844 prostate cancers identifies ZNRF3 loss as a predictor of metastatic relapse.
Nat Commun
13
2021
AR, Driver gene, MYC, PRC1/2, PRKDC, RNA, SNVs, TP53, WNT, ZNRF3, ZNRF3 mRNA, cancer, enhancer, mCRPC, metastatic, castration-resistant prostate cancer, prostate cancer, prostate cancers, tumors
Biomarkers, Tumor, Cell Cycle, Cell Cycle Proteins, Gene Expression Regulation, Neoplastic, Humans, Male, Mutation, Neoplasm Recurrence, Local, Prevalence, Prognosis, Prostatic Neoplasms, Ubiquitin-Protein Ligases
Author NameAffiliation
Michael FraserUniversity of Toronto
Michael FraserPrincess Margaret Cancer Centre
Michael FraserOntario Institute for Cancer Research
Julie LivingstoneUniversity of California los angeles
Julie LivingstoneUniversity of California los angeles
Julie LivingstoneInstitute for Precision Health, University of California los angeles
Julie LivingstoneJonsson Comprehensive Cancer Centre, University of California los angeles
Jeffrey L WranaLunenfeld Research Institute, Mount Sinai Hospital
Jeffrey L WranaMount Sinai Hospital
Antonio FinelliUniversity of Toronto
Antonio FinelliPrincess Margaret Cancer Centre
Antonio FinelliPrincess Margaret Cancer Centre
Housheng Hansen HePrincess Margaret Cancer Centre
Housheng Hansen HeUniversity of Toronto
Theodorus H van der KwastUniversity of Toronto
Theodorus H van der KwastUniversity Health Network
Alexandre R ZlottaUniversity of Toronto
Alexandre R ZlottaPrincess Margaret Cancer Centre
Alexandre R ZlottaLunenfeld Research Institute, Mount Sinai Hospital
Alexandre R ZlottaMount Sinai Hospital
Robert G BristowUniversity of Toronto
Robert G BristowManchester Cancer Research Centre
Robert G BristowUniversity of Manchester
Paul C BoutrosUniversity of California los angeles
Paul C BoutrosUniversity of California los angeles
Paul C BoutrosInstitute for Precision Health, University of California los angeles
Paul C BoutrosJonsson Comprehensive Cancer Centre, University of California los angeles
Paul C BoutrosUniversity of Toronto
Paul C BoutrosUniversity of Toronto
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