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Paper Details

Deletion and replacement of long genomic sequences using prime editing.
Nat Biotechnol
73
2022
Cas9, Cas9 nuclease, FAH, Fah gene, PE, PE guide RNAs, PE-Cas9, PEDAR, endogenous loci, exogenous DNA template, genomic deletions, genomic fragment, human, indels, long genomic sequences, mouse, pegRNAs, reporter system, reverse transcriptase, target sequences, tyrosinemia
Author NameAffiliation
Tingting JiangRNA Therapeutics Institute, University of Massachusetts Medical School
Xiao-Ou ZhangUniversity of Massachusetts Medical School
Xiao-Ou ZhangTongji University
Zhiping WengUniversity of Massachusetts Medical School
Zhiping WengUniversity of Massachusetts Medical School
Wen XueRNA Therapeutics Institute, University of Massachusetts Medical School
Wen XueUniversity of Massachusetts Medical School
Wen XueUniversity of Massachusetts Medical School
Wen XueLi Weibo Institute for Rare Diseases Research, University of Massachusetts Medical School
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