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Paper Details

Orgo-Seq integrates single-cell and bulk transcriptomic data to identify cell type specific-driver genes associated with autism spectrum disorder.
Nat Commun
9
2022
15q11-13 duplications, 16p11, Cerebral organoids, RNA, autism spectrum disorder, bulk RNA, cell type, cell type-specific driver genes, cell types, immature neurons, neuropsychiatric disorders, organoids, progenitor cells, single, single-cell RNA sequence
Author NameAffiliation
Elaine T LimUniversity of Massachusetts Chan Medical School
Elaine T LimUniversity of Massachusetts Chan Medical School
Elaine T LimNeuroNexus Institute, University of Massachusetts Chan Medical School
Elaine T LimUniversity of Massachusetts Chan Medical School
Yingleong ChanUniversity of Massachusetts Chan Medical School
Yingleong ChanNeuroNexus Institute, University of Massachusetts Chan Medical School
Yingleong ChanUniversity of Massachusetts Chan Medical School
Christopher A WalshBroad Institute of MIT and Harvard
Christopher A WalshHarvard Medical School
Christopher A WalshHarvard Medical School
Christopher A WalshHoward Hughes Medical Institute
Christopher A WalshManton Center for Orphan Disease Research, Boston Children's Hospital
Christopher A WalshBoston Children's Hospital
Christopher A WalshBroad Institute of MIT and Harvard
Christopher A WalshBoston Children's Hospital
Christopher A WalshManton Center for Orphan Disease Research, Boston Children's Hospital
Christopher A WalshHoward Hughes Medical Institute
Christopher A WalshHarvard Medical School
Christopher A WalshHarvard Medical School
Soumya RaychaudhuriBroad Institute of MIT and Harvard
Soumya RaychaudhuriUniversity of Manchester
Soumya RaychaudhuriBrigham and Women's Hospital and Harvard Medical School
Soumya RaychaudhuriCenter for Data Sciences, Brigham and Women's Hospital and Harvard Medical School
Soumya RaychaudhuriBroad Institute of MIT and Harvard
Soumya RaychaudhuriCenter for Data Sciences, Brigham and Women's Hospital and Harvard Medical School
Soumya RaychaudhuriBrigham and Women's Hospital and Harvard Medical School
Soumya RaychaudhuriUniversity of Manchester
Joel N HirschhornBlavatnik Institute, Harvard Medical School
Joel N HirschhornCenter for Basic and Translational Obesity Research, Boston Children's Hospital
Joel N HirschhornBoston Children's Hospital
Joel N HirschhornBroad Institute of MIT and Harvard
Joel N HirschhornBlavatnik Institute, Harvard Medical School
Joel N HirschhornBroad Institute of MIT and Harvard
Joel N HirschhornBoston Children's Hospital
Joel N HirschhornCenter for Basic and Translational Obesity Research, Boston Children's Hospital
James F GusellaBlavatnik Institute, Harvard Medical School
James F GusellaHarvard Stem Cell Institute, Harvard University
James F GusellaBroad Institute of MIT and Harvard
James F GusellaCenter for Genomic Medicine, Massachusetts General Hospital
George M ChurchBlavatnik Institute, Harvard Medical School
George M ChurchWyss Institute for Biologically Inspired Engineerin, Harvard University
George M ChurchBlavatnik Institute, Harvard Medical School
George M ChurchWyss Institute for Biologically Inspired Engineerin, Harvard University
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