Skip to Main Content

Paper Details

Prostate cancer-associated SPOP mutations confer resistance to BET inhibitors through stabilization of BRD4.
Nat Med
217
2017
AR, BET, BET protein, BET proteins, BRD2, BRD3, BRD4, BRDT, ERG, I-BET, JQ1, Prostate cancer, SPOP, SPOP mutants, SPOP mutations, bromodomain, bromodomain and extraterminal, c-Myc, cancer, cullin-3SPOP, human, leukemia, organoids, patients, prostate cancer, prostate cancer cell lines, testis-specific isoform, tumor
Author NameAffiliation
Ling HuangCancer Research Institute, Beth Israel Deaconess Medical Center, Harvard Medical School
Francisco BecaBeth Israel Deaconess Medical Center, Harvard Medical School
Mirjam BlattnerSandra and Edward Meyer Cancer Center, Weill Cornell Medical College
Jun QiDana-Farber Cancer Institute, Harvard Medical School
Jun QiHarvard Medical School
Andrew H BeckBeth Israel Deaconess Medical Center, Harvard Medical School
Liewei WangMayo Clinic
Peter J WildInstitute of Pathology and Molecular Pathology, University Hospital Zurich
Levi A GarrawayDana-Farber Cancer Institute, Harvard Medical School
Levi A GarrawayDana-Farber Cancer Institute, Harvard Medical School
Mark A RubinInstitute for Precision Medicine and Department of Pathology and Laboratory Medicine, Weill Cornell Medical College
Mark A RubinSandra and Edward Meyer Cancer Center, Weill Cornell Medical College
Mark A RubinInstitute for Precision Medicine and Department of Pathology and Laboratory Medicine, Weill Cornell Medical College
Mark A RubinSandra and Edward Meyer Cancer Center, Weill Cornell Medical College
Christopher E BarbieriSandra and Edward Meyer Cancer Center, Weill Cornell Medical College
Christopher E BarbieriSandra and Edward Meyer Cancer Center, Weill Cornell Medical College
Senthil K MuthuswamyCancer Research Institute, Beth Israel Deaconess Medical Center, Harvard Medical School
Jiaoti HuangDuke University School of Medicine
James E BradnerDana-Farber Cancer Institute, Harvard Medical School
James E BradnerHarvard Medical School
  • 1 - 20

Datasets