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Paper Details

Combination Therapy With MDM2 and MEK Inhibitors Is Effective in Patient-Derived Models of Lung Adenocarcinoma With Concurrent Oncogenic Drivers and MDM2 Amplification.
J Thorac Oncol
3
2023
A549, A549 (KRAS) cells, ALK, BIM, ECLC5-GLx, EGFR, EGFRex19del, EGFRex19del/MDM2amp, ERK, KRAS, L13BS1, LUAD, LUAD12c, LUADs, LX-285, Lung Adenocarcinoma, MAPK, MDM2, MDM2amp, MEK, MET, METex14, METex14/, PUMA, Patient, Patient-, RET, SW1573, TP53, TRIM33, TRIM33-RET/MDM2amp, capmatinib, cell lines, lung adenocarcinomas, milademetan, oncogenic driver mutations, p53, patient, patient-derived LUAD models, patients, selpercatinib, trametinib, tumor, tumors
Author NameAffiliation
Umesh BhanotMemorial Sloan Kettering Cancer Center
Umesh BhanotMemorial Sloan Kettering Cancer Center
Alexander DrilonMemorial Sloan Kettering Cancer Center, Weill Cornell Medical College
Gregory J RielyMemorial Sloan Kettering Cancer Center, Weill Cornell Medical College
Elisa de StanchinaMemorial Sloan Kettering Cancer Center
Charles M RudinMemorial Sloan Kettering Cancer Center, Weill Cornell Medical College
Marc LadanyiMemorial Sloan Kettering Cancer Center
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