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Paper Details

IL15 modification enables CAR T cells to act as a dual targeting agent against tumor cells and myeloid-derived suppressor cells in GBM.
J Immunother Cancer
15
2023
B cells, CAR, CAR T cells, CAR-T cells, CAR., CAR.IL15f, CAR.IL15f T cells, CAR.IL15s, CD11b, CD11b+, CD11b+cells, CD8+, CD8+T cells, GBM, GBMs, IL13R2, IL13R2+, IL13R2-CARs, IL15, IL15-modified CAR T cells, IL15R, IL15Ra, IL15f, MDSC, MDSCs, NK, chimeric antigen receptor, chimeric antigen receptor T cells, glioblastoma, glioma, mice, murine, murine T cells, myeloid, B, myeloid, B, and dendritic cells, myeloid-derived suppressor cells, patients, peripheral and tumor-infiltrating immune cells, secretory IL15, syngeneic IL13R2+glioma models, tumor, tumor cells, tumors
Author NameAffiliation
Adam M SonabendNorthwestern University
Adam M SonabendNorthwestern Medicine Malnati Brain Tumor Institute of the Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University
Craig HorbinskiNorthwestern University
Craig HorbinskiNorthwestern Medicine Malnati Brain Tumor Institute of the Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University
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