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Paper Title
The tricyclic antidepressant amitriptyline inhibits D-cyclin transactivation and induces myeloma cell apoptosis by inhibiting histone deacetylases: in vitro and in silico evidence.
PubMed
Paper Journal Title
Mol Pharmacol
Paper Citation Count
45
Paper Publication Year
2011
Bio Mention
Amitriptyline, D, D-Cyclin, D-cyclin, H3, HDAC, HDAC2, HDAC3, -6, -7, and -8, HDAC7, HDACs, His192, His326, Leu293, Phe162, Phe221, amitriptyline, anxiety, cancer, cancer cell, caspase-3, cyclin D2, cyclin D2 promoter, depression, histone, histone 3, histone deacetylases, luciferase, multiple myeloma, myeloma, myeloma cell, p21, p27, patients, poly(ADP-ribose), poly(ADP-ribose) polymerase-1
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