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Paper Details

Multiplatform molecular profiling uncovers two subgroups of malignant peripheral nerve sheath tumors with distinct therapeutic vulnerabilities.
Nat Commun
5
2023
-catenin, CCND1, G1, G2, MPNST, MPNST-, MPNST-G1, MPNST-G2, MPNSTs, Malignant peripheral nerve sheath tumor, SHH, Schwann cell, Single, WNT, malignant cells, malignant peripheral nerve sheath tumors, neural crest, neurofibromatosis type 1-related malignancy, peripheral nerve sheath tumors, precursor-like cell, sarcoma, therapeutic, tumors
Author NameAffiliation
Suganth SuppiahPrincess Margaret Cancer Centre
Suganth SuppiahUniversity of Toronto
Vikas PatilPrincess Margaret Cancer Centre
Bharati MehaniCenter for Cancer Research, National Cancer Institute
Severa BundaPrincess Margaret Cancer Centre
Olivia SinghPrincess Margaret Cancer Centre
Shirin KarimiPrincess Margaret Cancer Centre
Qingxia WeiPrincess Margaret Cancer Centre
Farshad NassiriPrincess Margaret Cancer Centre
Farshad NassiriUniversity of Toronto
Trevor J PughOntario Institute for Cancer Research
Trevor J PughPrincess Margaret Cancer Centre, University Health Network
Trevor J PughUniversity of Toronto
Trevor J PughOntario Institute for Cancer Research
Trevor J PughUniversity of Toronto
Trevor J PughPrincess Margaret Cancer Centre, University Health Network
Gary D BaderUniversity of Toronto
Gary D BaderPrincess Margaret Cancer Centre, University Health Network
Gary D BaderUniversity of Toronto
Gary D BaderUniversity of Toronto
Kenneth AldapeCenter for Cancer Research, National Cancer Institute
Kenneth AldapeCenter for Cancer Research, National Cancer Institute
David A LargaespadaMasonic Cancer Center, University of Minnesota
David A LargaespadaUniversity of Minnesota
David A LargaespadaMasonic Cancer Center, University of Minnesota
David A LargaespadaUniversity of Minnesota
Gelareh ZadehPrincess Margaret Cancer Centre
Gelareh ZadehUniversity of Toronto
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