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Paper Details

K27M in canonical and noncanonical H3 variants occurs in distinct oligodendroglial cell lineages in brain midline gliomas.
Nat Genet
25
2022
-, /BMP-dependent progenitors, ACVR1, ACVR1 mutations, ACVR1-mutant pontine gliomas, BMP, H3, H3 variants, H3.1, H3.1K27M, H3.2, H3.3, H3.3K27M, H3K27me3, K27M-mutant gliomas, NKX6, NKX6-1, OPCs, PAX3, PRC2 landing sites, SHH, brain midline gliomas, cell of, chromatin, developmental genes, dorsal PAX3, dorsal PAX3/BMP-dependent progenitors, epigenomic, gliomas, histone, histone 3 K27M, histone 3 K27M-mutant gliomas, oligodendrocyte precursor cells, oligodendroglial cell lineages, origin, prosomere 2-derived lineages, single, thalamic gliomas, tumors
Author NameAffiliation
Selin JessaMcGill University
Selin JessaLady Davis Institute for Medical Research, Jewish General Hospital
Maria C VladoiuUniversity of Toronto
Maria C VladoiuThe Hospital for Sick Children
Maria C VladoiuThe Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children
Livia GarziaThe Research Institute of the McGill University Health Centre
Livia GarziaMcGill University
Keith L LigonBoston Children's Hospital and Brigham and Women's Hospital, Harvard Medical School
Keith L Ligon
Keith L LigonDana-Farber Cancer Institute
Pratiti Bandopadhayay
Pratiti BandopadhayayHarvard Medical School
Pratiti BandopadhayayDana-Farber Cancer Institute
Michael D TaylorThe Hospital for Sick Children
Michael D TaylorThe Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children
Michael D TaylorThe Hospital for Sick Children
Michael D TaylorThe Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children
Stephen C MackSt Jude Children's Research Hospital
Stephen C MackSt Jude Children's Research Hospital
Nada JabadoMcGill University
Nada JabadoMcGill University, and The Research Institute of the McGill University Health Centre
Nada JabadoMcGill University
Nada JabadoMcGill University
Nada JabadoMcGill University, and The Research Institute of the McGill University Health Centre
Nada JabadoMcGill University
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