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Paper Details

The loss-of-function PCSK9Q152H variant increases ER chaperones GRP78 and GRP94 and protects against liver injury.
J Clin Invest
24
2021
CVD, ER chaperones, ER stress, ERSD, GRP78, GRP94, Gln152His, Gln152His variation, PCSK9, PCSK9 variant, PCSK9Q152H, PCSK9Q152H variant, PCSK9Q152H variation, cardiovascular disease, cholesterol, hypocholesterolemia, liver hepatocytes, liver injury, low-density lipoprotein, mice, mouse, patients, proPCSK9, proprotein convertase subtilisin/kexin type 9
Author NameAffiliation
Guillaume ParéPopulation Health Research Institute and Departments of Medicine, McMaster University
Renata Pasqualini
Wadih ArapRutgers New Jersey Medical School and Rutgers Cancer Institute of New Jersey
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