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Paper Details

Mediator kinase inhibition further activates super-enhancer-associated genes in AML.
Nature
269
2015
AML, AML cells, BRD4, CA-insensitive cell lines, CA-sensitive AML cell lines, CDK19, CDK7, CDK8, CEBPA, ETV6, I-BET151, IRF1, IRF8, Mediator complex, Mediator kinase, Mediator kinases, Mediator-associated kinases, SE, SE-associated genes, SEs, Super-enhancers, anti, cortistatin A, cyclin-dependent kinase 8, enhancers, leukaemia, leukaemia cells, leukaemic, myeloid leukaemia, myeloid leukaemia (AML) cells, oncogenes, specific cell types, super-enhancer-associated genes, transcription factors, tumour
Author NameAffiliation
Amanda L ChristieDana-Farber Cancer Institute
Christopher C EbmeierUniversity of Colorado
Scott A ArmstrongMemorial Sloan Kettering Cancer Center
Scott A ArmstrongMemorial Sloan Kettering Cancer Center
Dylan J TaatjesUniversity of Colorado
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