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Paper Details

Degradation of GSPT1 causes TP53-independent cell death in leukemia while sparing normal hematopoietic stem cells.
J Clin Invest
16
2022
CRL4CRBN, Crbn, GSPT1, GSPT1-, Gspt1, TP53, TP53-mutant acute myeloid leukemia, acute myeloid leukemia, amino acids, cancer, hematopoietic stem cells, leukemia, long-term hematopoietic stem cells, mice, mouse, ubiquitin
Author NameAffiliation
Jessica A GasserDana-Farber Cancer Institute
Jessica A GasserBroad Institute of MIT and Harvard
Steven A CarrBroad Institute of MIT and Harvard
Steven A CarrBroad Institute of MIT and Harvard
Benjamin L EbertDana-Farber Cancer Institute
Benjamin L EbertBroad Institute of MIT and Harvard
Benjamin L EbertHoward Hughes Medical Institute
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