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Paper Details

Structure of PDE3A-SLFN12 complex reveals requirements for activation of SLFN12 RNase.
Nat Commun
31
2021
C, DNMDP, PDE3A, RNase, SLFN12, SLFN12 RNase, SLFN12 protein, cancer, cancer cell, cancer cells, phosphodiesterase PDE3A, velcrin, velcrins
Author NameAffiliation
Xiaoyun WuBroad Institute of MIT and Harvard
Malvina PapanastasiouBroad Institute of MIT and Harvard
James MullahooBroad Institute of MIT and Harvard
Federica PiccioniBroad Institute of MIT and Harvard
Federica PiccioniMerck Research Laboratories
Timothy A LewisCenter for the Development of Therapeutics, Broad Institute of MIT and Harvard
Steven A CarrBroad Institute of MIT and Harvard
Steven A CarrBroad Institute of MIT and Harvard
Andrew D CherniackBroad Institute of MIT and Harvard
Andrew D CherniackDana-Farber Cancer Institute
Andrew D CherniackBroad Institute of MIT and Harvard
Andrew D CherniackDana-Farber Cancer Institute
Matthew MeyersonBroad Institute of MIT and Harvard
Matthew MeyersonDana-Farber Cancer Institute
Matthew MeyersonBroad Institute of MIT and Harvard
Matthew MeyersonDana-Farber Cancer Institute
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