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Paper Details

Exportin 1 inhibition prevents neuroendocrine transformation through SOX2 down-regulation in lung and prostate cancers.
Sci Transl Med
5
2023
EGFR, Exportin 1, NE, RB1, SCLC, SOX2, Selinexor, TP53, TP53/, adenocarcinoma, aromatase, enzalutamide, exportin 1, lung and prostate adenocarcinoma, lung and prostate adenocarcinoma cell lines, lung and prostate adenocarcinomas, lung and prostate cancers, lung and prostate pretransformation adenocarcinomas, lung cancer, osimertinib, patient, patient-derived xenograft (PDX, selinexor, sensitized NE-transformed lung and prostate small cell carcinoma PDXs, small cell lung cancer
Author NameAffiliation
Andrew ChowMemorial Sloan Kettering Cancer Center
Andrew ChowWeill Cornell Medical College
Andrew ChowParker Institute for Cancer Immunotherapy, Memorial Sloan Kettering Cancer Center
Umesh BhanotMemorial Sloan Kettering Cancer Center
Umesh BhanotMemorial Sloan Kettering Cancer Center
Elisa de StanchinaMemorial Sloan Kettering Cancer Center
Colm MorrisseyUniversity of Washington
Colm MorrisseyUniversity of Washington
Michael C HaffnerDivisions of Human Biology and Clinical Research, Fred Hutchinson Cancer Center
Michael C HaffnerUniversity of Washington
Richard KocheCenter for Epigenetics Research, Memorial Sloan Kettering Cancer Center
Richard KocheCenter for Epigenetics Research, Memorial Sloan Kettering Cancer Center
Charles L SawyersMemorial Sloan Kettering Cancer Center
Charles L SawyersHoward Hughes Medical Institute, Memorial Sloan Kettering Cancer Center
Charles M RudinMemorial Sloan Kettering Cancer Center
Charles M RudinWeill Cornell Medical College
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