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Paper Details

Structure-based discovery of prescription drugs that interact with the norepinephrine transporter, NET.
Proc Natl Acad Sci U S A
94
2011
2-adrenergic receptor, Alzheimer's, LeuT, NET, NET model, diabetes, leucine, leucine transporter, norepinephrine, norepinephrine transporter, phenformin, presynaptic neurons, primary binding site, prokaryotic NET homolog, talsaclidine, tranylcypromine, tuaminoheptane
Algorithms, Amino Acid Sequence, Bacterial Proteins, Binding Sites, Biological Transport, Computational Biology, Drug Discovery, HEK293 Cells, Humans, Kinetics, Models, Molecular, Molecular Sequence Data, Molecular Structure, Norepinephrine, Norepinephrine Plasma Membrane Transport Proteins, Plasma Membrane Neurotransmitter Transport Proteins, Prescription Drugs, Protein Binding, Protein Structure, Tertiary, Sequence Homology, Amino Acid
Author NameAffiliation
Avner Schlessingerand California Institute for Quantitative Biosciences, University of California san francisco
Avner Schlessingerand California Institute for Quantitative Biosciences, University of California san francisco
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Datasets

KEGGKyoto encyclopedia of genes and genomes: databases on genes, proteins, and metabolic pathwaysLink
KEGGKyoto encyclopedia of genes and genomes: databases on genes, proteins, and metabolic pathwaysLink
KEGGKyoto encyclopedia of genes and genomes: databases on genes, proteins, and metabolic pathwaysLink
KEGGKyoto encyclopedia of genes and genomes: databases on genes, proteins, and metabolic pathwaysLink
KEGGKyoto encyclopedia of genes and genomes: databases on genes, proteins, and metabolic pathwaysLink
KEGGKyoto encyclopedia of genes and genomes: databases on genes, proteins, and metabolic pathwaysLink
KEGGKyoto encyclopedia of genes and genomes: databases on genes, proteins, and metabolic pathwaysLink
KEGGKyoto encyclopedia of genes and genomes: databases on genes, proteins, and metabolic pathwaysLink
KEGGKyoto encyclopedia of genes and genomes: databases on genes, proteins, and metabolic pathwaysLink
KEGGKyoto encyclopedia of genes and genomes: databases on genes, proteins, and metabolic pathwaysLink
KEGGKyoto encyclopedia of genes and genomes: databases on genes, proteins, and metabolic pathwaysLink
KEGGKyoto encyclopedia of genes and genomes: databases on genes, proteins, and metabolic pathwaysLink
KEGGKyoto encyclopedia of genes and genomes: databases on genes, proteins, and metabolic pathwaysLink
KEGGKyoto encyclopedia of genes and genomes: databases on genes, proteins, and metabolic pathwaysLink
KEGGKyoto encyclopedia of genes and genomes: databases on genes, proteins, and metabolic pathwaysLink