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Paper Details

Nicotinamide phosphoribosyltransferase inhibitors selectively induce apoptosis of AML stem cells by disrupting lipid homeostasis.
Cell Stem Cell
45
2021
AML, AML cells, AML stem cells, KPT-9274, LSC, LSCs, NAMPT, Nicotinamide, SCD, SREBP, acute myeloid leukemia, dipyridamole, hematopoietic stem and progenitor cells, leukemic, leukemic stem cells, monounsaturated fatty acids, nicotinamide, nicotinamide phosphoribosyltransferase, saturated fatty acids, stearoyl-CoA, sterol, sterol regulatory-element binding protein, sterol regulatory-element binding protein (SREBP)-regulated genes
Author NameAffiliation
Gary D BaderPrincess Margaret Cancer Centre, University Health Network
Angelo D'AlessandroUniversity of Colorado Denver
Angelo D'AlessandroUniversity of Colorado Denver
John E DickPrincess Margaret Cancer Centre, University Health Network, University of Toronto
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