Skip to Main Content

Paper Details

SARS-CoV-2 infects blood monocytes to activate NLRP3 and AIM2 inflammasomes, pyroptosis and cytokine release.
Res Sq
36
2021
AIM2 inflammasomes, CD16, COVID, COVID-19, COVID-19 disease, Fc receptor, GSDMD, IL-1 family cytokines, Monocyte, Monocytes, NLRP3, SARS, SARS-, SARS-CoV, SARS-CoV-2, blood monocytes, caspase-1, double-stranded RNA, eQTLs, expression quantitative trait loci, fluorescent reporter gene, gasdermin D, immune cells, infected cells, infected epithelial cells, infected monocyte, inflammation, macrophages, monocytes, multiorgan failure, patient, patients, pyroptosis, respiratory distress, subgenomic RNA, systemic inflammation, tissue
Author NameAffiliation
Douglas S KwonRagon Institute, Massachusetts General Hospital, Massachusetts Institute of Technology, Harvard Medical School
Douglas S KwonRagon Institute, Massachusetts General Hospital, Massachusetts Institute of Technology, Harvard Medical School
Chris SanderDana-Farber Cancer Institute and Department of Cell Biology, Harvard Medical School
Chris SanderDana-Farber Cancer Institute and Department of Cell Biology, Harvard Medical School
Michael R FilbinMassachusetts General Hospital Institute for Patient Care
Judy LiebermanBoston Children's Hospital
Judy LiebermanHarvard Medical School
  • 1 - 7

Datasets

Release 1.2