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Paper Details

Type I interferons and microbial metabolites of tryptophan modulate astrocyte activity and central nervous system inflammation via the aryl hydrocarbon receptor.
Nat Med
889
2016
AHR, Astrocytes, CNS autoimmunity, CNS inflammation, CNS lesions, EAE, IFN, IFN-I, IFN-Is, MS, SOCS2, Type I interferons, ampicillin, aryl hydrocarbon, aryl hydrocarbon receptor, astrocyte, astrocytes, autoimmune encephalomyelitis, central nervous system inflammation, indole, indole-3-aldehyde, indole-3-propionic acid, indoxyl-3-sulfate, interferon, mice, multiple sclerosis, patients, suppressor of cytokine signaling 2, tryptophan, tryptophanase, type I interferons
Author NameAffiliation
Jorge I AlvarezUniversity of Pennsylvania
Nathalie PochetAnn Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School
Nathalie PochetBroad Institute of the Massachusetts Institute of Technology (MIT) and Harvard University
Nathalie PochetAnn Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School
Nathalie PochetBroad Institute of the Massachusetts Institute of Technology (MIT) and Harvard University
Clary B ClishBroad Institute of MIT and Harvard University
Clary B ClishBroad Institute of MIT and Harvard University
Marco PrinzInstitute of Neuropathology, University of Freiburg
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