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Paper Details

Transcriptional Dysregulation Underlies Both Monogenic Arrhythmia Syndrome and Common Modifiers of Cardiac Repolarization.
Circulation
9
2023
BrS, Brugada syndrome, Cas9, G145R, Monogenic Arrhythmia Syndrome, PDGF, PDGF receptor, PI3K, RNA, T-box transcription factor 5, TBX5, TBX5-G145R, Tbx5, arrhythmia, arrhythmogenesis, cardiac sodium channel gene, cardiac transcription factor, electrophysiologic abnormalities, iPSC, iPSC-CMs, iPSC-derived cardiomyocytes, iPSCs, induced pluripotent stem cells, inherited arrhythmia syndrome, phosphoinositide 3-kinase, platelet-derived growth factor, platelet-derived growth factor receptor, serum PDGF, sodium, sodium voltage-gated channel alpha subunit 5
Author NameAffiliation
Kevin BersellVanderbilt University
Jonathan D MosleyVanderbilt University
Andrew M GlazerVanderbilt University
Quinn S WellsVanderbilt University
Quinn S WellsVanderbilt University
Quinn S WellsVanderbilt University
Ramachandran S VasanBoston University School of Medicine
Qiong YangBoston University School of Medicine
Robert E GersztenCardiovascular Research Center (E.J.B., Beth Israel Deaconess Hospital
Robert E GersztenBeth Israel Deaconess Hospital
Christian M ShafferVanderbilt University
Thomas J WangVanderbilt University
Thomas J WangVanderbilt University
Dan M RodenVanderbilt University
Dan M RodenVanderbilt University
Dan M RodenVanderbilt University
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Release 1.2