G, GFP, GTPase, Rab1, TRAPP, TRAPP complex, TRAPP complex subunits, TRAPP complexes, TRAPP subunits, TRAPPC4, TRAPPC4 protein, TRAPPC4 variant, VSVG, autophagosomes, children, chr11, developmental delay, exon 3, fibroblasts, full-length transcript, g, guanine nucleotide, guanine nucleotide exchange factor, microcephaly, neurodevelopmental disorders, neurological disorders, non, polyacrylamide, progressive cortical and cerebellar atrophy, sensorineural deafness, spastic quadriparesis, syndromic intellectual disability, transport protein particle, ts045, variant hotspot region, wild, wild-type TRAPPC4, yeast, yeast Trs23 orthologue, yeast trs23, yeast trs23 temperature sensitive variant