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Paper Details

WEE1 inhibition enhances the antitumor immune response to PD-L1 blockade by the concomitant activation of STING and STAT1 pathways in SCLC.
Cell Rep
41
2022
AZD1775, CCL5, CD8, CD8 cytotoxic T cell, CXCL10, IFN, IFN-?, IRF3, MYC, PD-L1, SCLC, SCLC models, SCLCs, STAT1, STING, Small cell lung cancers, TBK1, WEE1, cytotoxic T cells, immunocompetent SCLC genetically engineered mouse models, mouse, tumor, type I and II interferon, type I interferons
Author NameAffiliation
Andrew ChowMemorial Sloan Kettering Cancer Center, Mortimer B. Zuckerman Research Center
Elisa de StanchinaMemorial Sloan Kettering Cancer Center
Charles M RudinMemorial Sloan Kettering Cancer Center, Mortimer B. Zuckerman Research Center, USA Weill Cornell Medical College
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Release 1.2