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Paper Details

Increased PDGFRB and NF-κB signaling caused by highly prevalent somatic mutations in intracranial aneurysms.
Sci Transl Med
2
2023
ERK, IA, IAs, Intracranial aneurysms, NF-B, PDGFRB, arterial dilatation, fusiform and saccular IAs, fusiform aneurysms, fusiform-like dilatation of the basilar artery, inflammation-related gene, intracranial aneurysms, mice, multiple, mutant PDGFRBs, patients, saccular, signaling genes, subarachnoid hemorrhage, sunitinib, tyrosine, tyrosine kinase, vessels
Author NameAffiliation
Rieko OyamaRIKEN Center for Brain Science
Yoichiro KamataniUniversity of Tokyo
Motoo NaganeKyorin University
Kenjiro KosakiCenter for Medical Genetics, Keio University Faculty of Medicine
Hidewaki NakagawaRIKEN Center for Integrative Medical Sciences
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