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Paper Details

A novel antifolate suppresses growth of FPGS-deficient cells and overcomes methotrexate resistance.
Life Sci Alliance
1
2023
-deficient cells, 5-fluorouracil, CRC, Cancer, Cancer cells, FPGS, FPGS-deficient cells, colorectal cancer, dihydrofolate, dihydrofolate reductase, folate, folates, folylpolyglutamate, folylpolyglutamate synthetase, leukemia, methotrexate, one-carbon, patient, polyglutamylation deficiency
Author NameAffiliation
Alexandre M J J BonvinUtrecht University
Alexandre M J J BonvinUtrecht University
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Release 1.2