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Paper Details

IFN-α blockade during ART-treated SIV infection lowers tissue vDNA, rescues immune function, and improves overall health.
JCI Insight
8
2022
CD8+, CD8+ T cell, HIV, HIV infection, IFN-, IFN-?, IL-12, SIV, SIV infection, TGF-?, TI-IFN, TI-IFN-inducible genes, TI-IFNs, Type I IFNs, anemia, anti-IFN-, genes, heme, induced effector CD8+ T cell, monocyte activation genes, nonhuman, rhesus macaques, vDNA, viral infections, weight
Author NameAffiliation
Jacob D EstesFrederick National Laboratory for Cancer Research, Leidos Biomedical Research Inc.
Jacob D EstesVaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University
Steven G DeeksUniversity of California san francisco
Steven G DeeksUniversity of California san francisco
Peter W HuntUniversity of California san francisco
Rafick-Pierre SekalyCase Western Reserve University
Rafick-Pierre SekalyEmory University
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Release 1.2