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Paper Details

Blockade of the immunosuppressive KIR2DL5/PVR pathway elicits potent human NK cell-mediated antitumor immunity.
J Clin Invest
13
2022
B, Cancer, ERK1/2, ITIM, ITSM, KIR, KIR2DL5, KIR2DL5+, KIR2DL5+ immune cells, NF-, NK, NK cell, NK cell-based humanized tumor models, NK cells, PVR, PVR receptors, SHP-1, SHP-2, TIGIT, Vav1, cancers, human, human NK cells, human killer cell, immunoglobulin-like receptor, humanized, p90RSK, target cells, tumor, tumors, tyrosine
Author NameAffiliation
Winfried Edelmann
Deyou ZhengAlbert Einstein College of Medicine
Deyou Zheng
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Release 1.2