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Paper Details

Radiomics-Derived Brain Age Predicts Functional Outcome After Acute Ischemic Stroke.
Neurology
11
2023
Acute Ischemic Stroke, RBA, acute stroke, diabetes mellitus, hypertension, ischemic stroke, patients, stroke
Author NameAffiliation
John W ColeFrom the J. Philip Kistler Stroke Research Center (M.B., A.A. Martinos Center for Biomedical Imaging (A. Dalca, and Henry and Allison McCance Center for Brain Health (J. Rosand), Massachusetts General Hospital, Harvard Medical School, Inserm, U2 and Institut Pasteur de Lille (M.G.), CNRS, Lille University, Massachusetts Institute of Technology, Brigham and Women's Hospital, University of British Columbia, University of Maryland School of Medicine and Veterans Affairs Maryland Health Care System, University of Campinas (UNICAMP) and the Brazilian Institute of Neuroscience and Neurotechnology (BRAINN), Paracelsus Medical University, Washington University School of Medicine, Washington University School of Medicine & Barnes-Jewish Hospital, Institute of Neuroscience and Physiology, Sahlgrenska Academy at University of Gothenburg, Sahlgrenska University Hospital, IMIM-Hospital del Mar (Institut Hospital del Mar d'Investigacions M`ediques), Universitat Autonoma de Barcelona, Experimental Neurology and Leuven Research Institute for Neuroscience and Disease (LIND), KU Leuven - University of Leuven, VIB Vesalius Research Center, University Hospitals Leuven, Belgium School of Medicine and Public Health (C.R.L.), University of Newcastle, John Hunter Hospital, University of Maryland School of Medicine, Baltimore Department of Pharmacotherapy and Translational Research and Center for Pharmacogenomics (C.W.M.), University of Florida, Mayo Clinic, Universitatsmedizin Rostock, Clinical Division of Neurogeriatrics, Medical University Graz, Austria Center for Genomic Medicine (J. Rosand), Boston Broad Institute (J. Rosand), MA Department of Neurology and Evelyn F. McKnight Brain Institute (J. Roquer, Miller School of Medicine, University of Miami, FL Institute of Cardiovascular Research (P.S.), Royal Holloway University of London (ICR2UL), UK St Peter's and Ashford Hospitals, Jagiellonian University Medical College, Helsinki University Central Hospital, Florey Institute of Neuroscience and Mental Health, University of Cincinnati College of Medicine, Lund University, Skane University Hospital, University of Virginia, VA University of Technology Sydney (J.M.), Institute of Biomedicine, University of Gothenburg
Patrick F McArdleFrom the J. Philip Kistler Stroke Research Center (M.B., A.A. Martinos Center for Biomedical Imaging (A. Dalca, and Henry and Allison McCance Center for Brain Health (J. Rosand), Massachusetts General Hospital, Harvard Medical School, Inserm, U2 and Institut Pasteur de Lille (M.G.), CNRS, Lille University, Massachusetts Institute of Technology, Brigham and Women's Hospital, University of British Columbia, University of Maryland School of Medicine and Veterans Affairs Maryland Health Care System, University of Campinas (UNICAMP) and the Brazilian Institute of Neuroscience and Neurotechnology (BRAINN), Paracelsus Medical University, Washington University School of Medicine, Washington University School of Medicine & Barnes-Jewish Hospital, Institute of Neuroscience and Physiology, Sahlgrenska Academy at University of Gothenburg, Sahlgrenska University Hospital, IMIM-Hospital del Mar (Institut Hospital del Mar d'Investigacions M`ediques), Universitat Autonoma de Barcelona, Experimental Neurology and Leuven Research Institute for Neuroscience and Disease (LIND), KU Leuven - University of Leuven, VIB Vesalius Research Center, University Hospitals Leuven, Belgium School of Medicine and Public Health (C.R.L.), University of Newcastle, John Hunter Hospital, University of Maryland School of Medicine, Baltimore Department of Pharmacotherapy and Translational Research and Center for Pharmacogenomics (C.W.M.), University of Florida, Mayo Clinic, Universitatsmedizin Rostock, Clinical Division of Neurogeriatrics, Medical University Graz, Austria Center for Genomic Medicine (J. Rosand), Boston Broad Institute (J. Rosand), MA Department of Neurology and Evelyn F. McKnight Brain Institute (J. Roquer, Miller School of Medicine, University of Miami, FL Institute of Cardiovascular Research (P.S.), Royal Holloway University of London (ICR2UL), UK St Peter's and Ashford Hospitals, Jagiellonian University Medical College, Helsinki University Central Hospital, Florey Institute of Neuroscience and Mental Health, University of Cincinnati College of Medicine, Lund University, Skane University Hospital, University of Virginia, VA University of Technology Sydney (J.M.), Institute of Biomedicine, University of Gothenburg
Caitrin W McDonoughFrom the J. Philip Kistler Stroke Research Center (M.B., A.A. Martinos Center for Biomedical Imaging (A. Dalca, and Henry and Allison McCance Center for Brain Health (J. Rosand), Massachusetts General Hospital, Harvard Medical School, Inserm, U2 and Institut Pasteur de Lille (M.G.), CNRS, Lille University, Massachusetts Institute of Technology, Brigham and Women's Hospital, University of British Columbia, University of Maryland School of Medicine and Veterans Affairs Maryland Health Care System, University of Campinas (UNICAMP) and the Brazilian Institute of Neuroscience and Neurotechnology (BRAINN), Paracelsus Medical University, Washington University School of Medicine, Washington University School of Medicine & Barnes-Jewish Hospital, Institute of Neuroscience and Physiology, Sahlgrenska Academy at University of Gothenburg, Sahlgrenska University Hospital, IMIM-Hospital del Mar (Institut Hospital del Mar d'Investigacions M`ediques), Universitat Autonoma de Barcelona, Experimental Neurology and Leuven Research Institute for Neuroscience and Disease (LIND), KU Leuven - University of Leuven, VIB Vesalius Research Center, University Hospitals Leuven, Belgium School of Medicine and Public Health (C.R.L.), University of Newcastle, John Hunter Hospital, University of Maryland School of Medicine, Baltimore Department of Pharmacotherapy and Translational Research and Center for Pharmacogenomics (C.W.M.), University of Florida, Mayo Clinic, Universitatsmedizin Rostock, Clinical Division of Neurogeriatrics, Medical University Graz, Austria Center for Genomic Medicine (J. Rosand), Boston Broad Institute (J. Rosand), MA Department of Neurology and Evelyn F. McKnight Brain Institute (J. Roquer, Miller School of Medicine, University of Miami, FL Institute of Cardiovascular Research (P.S.), Royal Holloway University of London (ICR2UL), UK St Peter's and Ashford Hospitals, Jagiellonian University Medical College, Helsinki University Central Hospital, Florey Institute of Neuroscience and Mental Health, University of Cincinnati College of Medicine, Lund University, Skane University Hospital, University of Virginia, VA University of Technology Sydney (J.M.), Institute of Biomedicine, University of Gothenburg
Caitrin W McDonoughFrom the J. Philip Kistler Stroke Research Center (M.B., A.A. Martinos Center for Biomedical Imaging (A. Dalca, and Henry and Allison McCance Center for Brain Health (J. Rosand), Massachusetts General Hospital, Harvard Medical School, Inserm, U2 and Institut Pasteur de Lille (M.G.), CNRS, Lille University, Massachusetts Institute of Technology, Brigham and Women's Hospital, University of British Columbia, University of Maryland School of Medicine and Veterans Affairs Maryland Health Care System, University of Campinas (UNICAMP) and the Brazilian Institute of Neuroscience and Neurotechnology (BRAINN), Paracelsus Medical University, Washington University School of Medicine, Washington University School of Medicine & Barnes-Jewish Hospital, Institute of Neuroscience and Physiology, Sahlgrenska Academy at University of Gothenburg, Sahlgrenska University Hospital, IMIM-Hospital del Mar (Institut Hospital del Mar d'Investigacions M`ediques), Universitat Autonoma de Barcelona, Experimental Neurology and Leuven Research Institute for Neuroscience and Disease (LIND), KU Leuven - University of Leuven, VIB Vesalius Research Center, University Hospitals Leuven, Belgium School of Medicine and Public Health (C.R.L.), University of Newcastle, John Hunter Hospital, University of Maryland School of Medicine, Baltimore Department of Pharmacotherapy and Translational Research and Center for Pharmacogenomics (C.W.M.), University of Florida, Mayo Clinic, Universitatsmedizin Rostock, Clinical Division of Neurogeriatrics, Medical University Graz, Austria Center for Genomic Medicine (J. Rosand), Boston Broad Institute (J. Rosand), MA Department of Neurology and Evelyn F. McKnight Brain Institute (J. Roquer, Miller School of Medicine, University of Miami, FL Institute of Cardiovascular Research (P.S.), Royal Holloway University of London (ICR2UL), UK St Peter's and Ashford Hospitals, Jagiellonian University Medical College, Helsinki University Central Hospital, Florey Institute of Neuroscience and Mental Health, University of Cincinnati College of Medicine, Lund University, Skane University Hospital, University of Virginia, VA University of Technology Sydney (J.M.), Institute of Biomedicine, University of Gothenburg
Jonathan RosandFrom the J. Philip Kistler Stroke Research Center (M.B., A.A. Martinos Center for Biomedical Imaging (A. Dalca, and Henry and Allison McCance Center for Brain Health (J. Rosand), Massachusetts General Hospital, Harvard Medical School, Inserm, U2 and Institut Pasteur de Lille (M.G.), CNRS, Lille University, Massachusetts Institute of Technology, Brigham and Women's Hospital, University of British Columbia, University of Maryland School of Medicine and Veterans Affairs Maryland Health Care System, University of Campinas (UNICAMP) and the Brazilian Institute of Neuroscience and Neurotechnology (BRAINN), Paracelsus Medical University, Washington University School of Medicine, Washington University School of Medicine & Barnes-Jewish Hospital, Institute of Neuroscience and Physiology, Sahlgrenska Academy at University of Gothenburg, Sahlgrenska University Hospital, IMIM-Hospital del Mar (Institut Hospital del Mar d'Investigacions M`ediques), Universitat Autonoma de Barcelona, Experimental Neurology and Leuven Research Institute for Neuroscience and Disease (LIND), KU Leuven - University of Leuven, VIB Vesalius Research Center, University Hospitals Leuven, Belgium School of Medicine and Public Health (C.R.L.), University of Newcastle, John Hunter Hospital, University of Maryland School of Medicine, Baltimore Department of Pharmacotherapy and Translational Research and Center for Pharmacogenomics (C.W.M.), University of Florida, Mayo Clinic, Universitatsmedizin Rostock, Clinical Division of Neurogeriatrics, Medical University Graz, Austria Center for Genomic Medicine (J. Rosand), Boston Broad Institute (J. Rosand), MA Department of Neurology and Evelyn F. McKnight Brain Institute (J. Roquer, Miller School of Medicine, University of Miami, FL Institute of Cardiovascular Research (P.S.), Royal Holloway University of London (ICR2UL), UK St Peter's and Ashford Hospitals, Jagiellonian University Medical College, Helsinki University Central Hospital, Florey Institute of Neuroscience and Mental Health, University of Cincinnati College of Medicine, Lund University, Skane University Hospital, University of Virginia, VA University of Technology Sydney (J.M.), Institute of Biomedicine, University of Gothenburg
Jonathan RosandFrom the J. Philip Kistler Stroke Research Center (M.B., A.A. Martinos Center for Biomedical Imaging (A. Dalca, and Henry and Allison McCance Center for Brain Health (J. Rosand), Massachusetts General Hospital, Harvard Medical School, Inserm, U2 and Institut Pasteur de Lille (M.G.), CNRS, Lille University, Massachusetts Institute of Technology, Brigham and Women's Hospital, University of British Columbia, University of Maryland School of Medicine and Veterans Affairs Maryland Health Care System, University of Campinas (UNICAMP) and the Brazilian Institute of Neuroscience and Neurotechnology (BRAINN), Paracelsus Medical University, Washington University School of Medicine, Washington University School of Medicine & Barnes-Jewish Hospital, Institute of Neuroscience and Physiology, Sahlgrenska Academy at University of Gothenburg, Sahlgrenska University Hospital, IMIM-Hospital del Mar (Institut Hospital del Mar d'Investigacions M`ediques), Universitat Autonoma de Barcelona, Experimental Neurology and Leuven Research Institute for Neuroscience and Disease (LIND), KU Leuven - University of Leuven, VIB Vesalius Research Center, University Hospitals Leuven, Belgium School of Medicine and Public Health (C.R.L.), University of Newcastle, John Hunter Hospital, University of Maryland School of Medicine, Baltimore Department of Pharmacotherapy and Translational Research and Center for Pharmacogenomics (C.W.M.), University of Florida, Mayo Clinic, Universitatsmedizin Rostock, Clinical Division of Neurogeriatrics, Medical University Graz, Austria Center for Genomic Medicine (J. Rosand), Boston Broad Institute (J. Rosand), MA Department of Neurology and Evelyn F. McKnight Brain Institute (J. Roquer, Miller School of Medicine, University of Miami, FL Institute of Cardiovascular Research (P.S.), Royal Holloway University of London (ICR2UL), UK St Peter's and Ashford Hospitals, Jagiellonian University Medical College, Helsinki University Central Hospital, Florey Institute of Neuroscience and Mental Health, University of Cincinnati College of Medicine, Lund University, Skane University Hospital, University of Virginia, VA University of Technology Sydney (J.M.), Institute of Biomedicine, University of Gothenburg
Daniel WooFrom the J. Philip Kistler Stroke Research Center (M.B., A.A. Martinos Center for Biomedical Imaging (A. Dalca, and Henry and Allison McCance Center for Brain Health (J. Rosand), Massachusetts General Hospital, Harvard Medical School, Inserm, U2 and Institut Pasteur de Lille (M.G.), CNRS, Lille University, Massachusetts Institute of Technology, Brigham and Women's Hospital, University of British Columbia, University of Maryland School of Medicine and Veterans Affairs Maryland Health Care System, University of Campinas (UNICAMP) and the Brazilian Institute of Neuroscience and Neurotechnology (BRAINN), Paracelsus Medical University, Washington University School of Medicine, Washington University School of Medicine & Barnes-Jewish Hospital, Institute of Neuroscience and Physiology, Sahlgrenska Academy at University of Gothenburg, Sahlgrenska University Hospital, IMIM-Hospital del Mar (Institut Hospital del Mar d'Investigacions M`ediques), Universitat Autonoma de Barcelona, Experimental Neurology and Leuven Research Institute for Neuroscience and Disease (LIND), KU Leuven - University of Leuven, VIB Vesalius Research Center, University Hospitals Leuven, Belgium School of Medicine and Public Health (C.R.L.), University of Newcastle, John Hunter Hospital, University of Maryland School of Medicine, Baltimore Department of Pharmacotherapy and Translational Research and Center for Pharmacogenomics (C.W.M.), University of Florida, Mayo Clinic, Universitatsmedizin Rostock, Clinical Division of Neurogeriatrics, Medical University Graz, Austria Center for Genomic Medicine (J. Rosand), Boston Broad Institute (J. Rosand), MA Department of Neurology and Evelyn F. McKnight Brain Institute (J. Roquer, Miller School of Medicine, University of Miami, FL Institute of Cardiovascular Research (P.S.), Royal Holloway University of London (ICR2UL), UK St Peter's and Ashford Hospitals, Jagiellonian University Medical College, Helsinki University Central Hospital, Florey Institute of Neuroscience and Mental Health, University of Cincinnati College of Medicine, Lund University, Skane University Hospital, University of Virginia, VA University of Technology Sydney (J.M.), Institute of Biomedicine, University of Gothenburg
Ona WuFrom the J. Philip Kistler Stroke Research Center (M.B., A.A. Martinos Center for Biomedical Imaging (A. Dalca, and Henry and Allison McCance Center for Brain Health (J. Rosand), Massachusetts General Hospital, Harvard Medical School, Inserm, U2 and Institut Pasteur de Lille (M.G.), CNRS, Lille University, Massachusetts Institute of Technology, Brigham and Women's Hospital, University of British Columbia, University of Maryland School of Medicine and Veterans Affairs Maryland Health Care System, University of Campinas (UNICAMP) and the Brazilian Institute of Neuroscience and Neurotechnology (BRAINN), Paracelsus Medical University, Washington University School of Medicine, Washington University School of Medicine & Barnes-Jewish Hospital, Institute of Neuroscience and Physiology, Sahlgrenska Academy at University of Gothenburg, Sahlgrenska University Hospital, IMIM-Hospital del Mar (Institut Hospital del Mar d'Investigacions M`ediques), Universitat Autonoma de Barcelona, Experimental Neurology and Leuven Research Institute for Neuroscience and Disease (LIND), KU Leuven - University of Leuven, VIB Vesalius Research Center, University Hospitals Leuven, Belgium School of Medicine and Public Health (C.R.L.), University of Newcastle, John Hunter Hospital, University of Maryland School of Medicine, Baltimore Department of Pharmacotherapy and Translational Research and Center for Pharmacogenomics (C.W.M.), University of Florida, Mayo Clinic, Universitatsmedizin Rostock, Clinical Division of Neurogeriatrics, Medical University Graz, Austria Center for Genomic Medicine (J. Rosand), Boston Broad Institute (J. Rosand), MA Department of Neurology and Evelyn F. McKnight Brain Institute (J. Roquer, Miller School of Medicine, University of Miami, FL Institute of Cardiovascular Research (P.S.), Royal Holloway University of London (ICR2UL), UK St Peter's and Ashford Hospitals, Jagiellonian University Medical College, Helsinki University Central Hospital, Florey Institute of Neuroscience and Mental Health, University of Cincinnati College of Medicine, Lund University, Skane University Hospital, University of Virginia, VA University of Technology Sydney (J.M.), Institute of Biomedicine, University of Gothenburg
Bradford B WorrallFrom the J. Philip Kistler Stroke Research Center (M.B., A.A. Martinos Center for Biomedical Imaging (A. Dalca, and Henry and Allison McCance Center for Brain Health (J. Rosand), Massachusetts General Hospital, Harvard Medical School, Inserm, U2 and Institut Pasteur de Lille (M.G.), CNRS, Lille University, Massachusetts Institute of Technology, Brigham and Women's Hospital, University of British Columbia, University of Maryland School of Medicine and Veterans Affairs Maryland Health Care System, University of Campinas (UNICAMP) and the Brazilian Institute of Neuroscience and Neurotechnology (BRAINN), Paracelsus Medical University, Washington University School of Medicine, Washington University School of Medicine & Barnes-Jewish Hospital, Institute of Neuroscience and Physiology, Sahlgrenska Academy at University of Gothenburg, Sahlgrenska University Hospital, IMIM-Hospital del Mar (Institut Hospital del Mar d'Investigacions M`ediques), Universitat Autonoma de Barcelona, Experimental Neurology and Leuven Research Institute for Neuroscience and Disease (LIND), KU Leuven - University of Leuven, VIB Vesalius Research Center, University Hospitals Leuven, Belgium School of Medicine and Public Health (C.R.L.), University of Newcastle, John Hunter Hospital, University of Maryland School of Medicine, Baltimore Department of Pharmacotherapy and Translational Research and Center for Pharmacogenomics (C.W.M.), University of Florida, Mayo Clinic, Universitatsmedizin Rostock, Clinical Division of Neurogeriatrics, Medical University Graz, Austria Center for Genomic Medicine (J. Rosand), Boston Broad Institute (J. Rosand), MA Department of Neurology and Evelyn F. McKnight Brain Institute (J. Roquer, Miller School of Medicine, University of Miami, FL Institute of Cardiovascular Research (P.S.), Royal Holloway University of London (ICR2UL), UK St Peter's and Ashford Hospitals, Jagiellonian University Medical College, Helsinki University Central Hospital, Florey Institute of Neuroscience and Mental Health, University of Cincinnati College of Medicine, Lund University, Skane University Hospital, University of Virginia, VA University of Technology Sydney (J.M.), Institute of Biomedicine, University of Gothenburg
Polina GollandFrom the J. Philip Kistler Stroke Research Center (M.B., A.A. Martinos Center for Biomedical Imaging (A. Dalca, and Henry and Allison McCance Center for Brain Health (J. Rosand), Massachusetts General Hospital, Harvard Medical School, Inserm, U2 and Institut Pasteur de Lille (M.G.), CNRS, Lille University, Massachusetts Institute of Technology, Brigham and Women's Hospital, University of British Columbia, University of Maryland School of Medicine and Veterans Affairs Maryland Health Care System, University of Campinas (UNICAMP) and the Brazilian Institute of Neuroscience and Neurotechnology (BRAINN), Paracelsus Medical University, Washington University School of Medicine, Washington University School of Medicine & Barnes-Jewish Hospital, Institute of Neuroscience and Physiology, Sahlgrenska Academy at University of Gothenburg, Sahlgrenska University Hospital, IMIM-Hospital del Mar (Institut Hospital del Mar d'Investigacions M`ediques), Universitat Autonoma de Barcelona, Experimental Neurology and Leuven Research Institute for Neuroscience and Disease (LIND), KU Leuven - University of Leuven, VIB Vesalius Research Center, University Hospitals Leuven, Belgium School of Medicine and Public Health (C.R.L.), University of Newcastle, John Hunter Hospital, University of Maryland School of Medicine, Baltimore Department of Pharmacotherapy and Translational Research and Center for Pharmacogenomics (C.W.M.), University of Florida, Mayo Clinic, Universitatsmedizin Rostock, Clinical Division of Neurogeriatrics, Medical University Graz, Austria Center for Genomic Medicine (J. Rosand), Boston Broad Institute (J. Rosand), MA Department of Neurology and Evelyn F. McKnight Brain Institute (J. Roquer, Miller School of Medicine, University of Miami, FL Institute of Cardiovascular Research (P.S.), Royal Holloway University of London (ICR2UL), UK St Peter's and Ashford Hospitals, Jagiellonian University Medical College, Helsinki University Central Hospital, Florey Institute of Neuroscience and Mental Health, University of Cincinnati College of Medicine, Lund University, Skane University Hospital, University of Virginia, VA University of Technology Sydney (J.M.), Institute of Biomedicine, University of Gothenburg
Natalia S RostFrom the J. Philip Kistler Stroke Research Center (M.B., A.A. Martinos Center for Biomedical Imaging (A. Dalca, and Henry and Allison McCance Center for Brain Health (J. Rosand), Massachusetts General Hospital, Harvard Medical School, Inserm, U2 and Institut Pasteur de Lille (M.G.), CNRS, Lille University, Massachusetts Institute of Technology, Brigham and Women's Hospital, University of British Columbia, University of Maryland School of Medicine and Veterans Affairs Maryland Health Care System, University of Campinas (UNICAMP) and the Brazilian Institute of Neuroscience and Neurotechnology (BRAINN), Paracelsus Medical University, Washington University School of Medicine, Washington University School of Medicine & Barnes-Jewish Hospital, Institute of Neuroscience and Physiology, Sahlgrenska Academy at University of Gothenburg, Sahlgrenska University Hospital, IMIM-Hospital del Mar (Institut Hospital del Mar d'Investigacions M`ediques), Universitat Autonoma de Barcelona, Experimental Neurology and Leuven Research Institute for Neuroscience and Disease (LIND), KU Leuven - University of Leuven, VIB Vesalius Research Center, University Hospitals Leuven, Belgium School of Medicine and Public Health (C.R.L.), University of Newcastle, John Hunter Hospital, University of Maryland School of Medicine, Baltimore Department of Pharmacotherapy and Translational Research and Center for Pharmacogenomics (C.W.M.), University of Florida, Mayo Clinic, Universitatsmedizin Rostock, Clinical Division of Neurogeriatrics, Medical University Graz, Austria Center for Genomic Medicine (J. Rosand), Boston Broad Institute (J. Rosand), MA Department of Neurology and Evelyn F. McKnight Brain Institute (J. Roquer, Miller School of Medicine, University of Miami, FL Institute of Cardiovascular Research (P.S.), Royal Holloway University of London (ICR2UL), UK St Peter's and Ashford Hospitals, Jagiellonian University Medical College, Helsinki University Central Hospital, Florey Institute of Neuroscience and Mental Health, University of Cincinnati College of Medicine, Lund University, Skane University Hospital, University of Virginia, VA University of Technology Sydney (J.M.), Institute of Biomedicine, University of Gothenburg
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