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Paper Details

Enhancer deletion and allelic effects define a regulatory molecular mechanism at the VLDLR cholesterol GWAS locus.
Human Molecular Genetics
5
2019
CRISPR, G allele, HEK293T kidney cells, IRF2, LDL-C, SMARCA2, Simpson, Simpson-Golabi-Behmel Syndrome, THP-1 monocyte, VLDLR, VLDLR cholesterol GWAS locus, cardiovascular disease, cas9, cell lines, cholesterol, enhancer element, expression quantitative trait locus, homozygous enhancer deletion cell lines, human, human HepG2 hepatocyte, intron, intron 3, intronic region, liver, low-density lipoprotein cholesterol, rs3780181, rs3780181 G allele, rs3780181 alleles, rs3780181-A risk allele
Author NameAffiliation
Karen L MohlkeUniversity of North Carolina
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Datasets

Release 1.2