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Paper Details

Epigenetic therapy activates type I interferon signaling in murine ovarian cancer to reduce immunosuppression and tumor burden.
Proc Natl Acad Sci U S A
187
2017
5-azacytidine, AZA, CD45+, CD8+, CD8+ T, CD8+ T and natural killer (NK) cells, DNA methyltransferase, DNMTi, EOC, Epithelial ovarian cancer, HDACi, Ovarian cancer, PD-1, T, T and NK cell, gynecological cancers, histone deacetylase, immune cells, immunosuppression, macrophages, mice, mouse, murine, myeloid-derived suppressor cells, ovarian cancer, ovarian cancers, tumor, tumor and immune cells, type I IFN, type I interferon, viral defense gene
Author NameAffiliation
Vipul Bhargava
Glenn S Cowley
Kurtis E Bachman
Stephen B BaylinThe Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Stephen B BaylinThe Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
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