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Paper Details

SETD2 Haploinsufficiency Enhances Germinal Center-Associated AICDA Somatic Hypermutation to Drive B-cell Lymphomagenesis.
Cancer Discov
13
2022
AICDA, B cell, B-cell, B-cell Lymphomagenesis, B-cell lymphomas, GC-derived lymphomas, H3K36me3, MYC, RNAPII, SETD2, SETD2 Haploinsufficiency, Setd2, Setd2 deficiency, Setd2 haploinsufficiency, Setd2-haploinsufficient germinal center B (GCB), cancers, cytosine, diffuse, diffuse large B-cell lymphomas, germinal center (GC) hyperplasia, histone methyltransferase, lymphoma, lymphoma cells, lymphomas, nontemplate strand, nontemplate strand DNA, transcribed genes, tumor
Author NameAffiliation
Cem Meydan
Cem Meydan
Cem MeydanThe HRH Prince Alwaleed Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine
Jeannie M CamarilloNorthwestern University
Jeannie M CamarilloNorthwestern University
Neil L KelleherNorthwestern University
Neil L KelleherNorthwestern University
Marcin Imielinski
Marcin ImielinskiCaryl and Israel Englander Institute for Precision Medicine and Meyer Cancer Center
Marcin Imielinski
Scott A ArmstrongDana-Farber Cancer Institute, Boston Children's Hospital and Harvard Medical School
Scott A ArmstrongDana-Farber Cancer Institute, Boston Children's Hospital and Harvard Medical School
Christopher E Mason
Christopher E MasonThe HRH Prince Alwaleed Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine
Christopher E Mason
Christopher E MasonThe Feil Family Brain and Mind Research Institute
Christopher E Mason
Christopher E MasonThe HRH Prince Alwaleed Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine
Christopher E Mason
Christopher E MasonThe Feil Family Brain and Mind Research Institute
Ari MelnickCornell University
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Release 1.2