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Paper Details

Leveraging polygenic enrichments of gene features to predict genes underlying complex traits and diseases.
Nat Genet
46
2023
CCR7, GWAS loci, LGR4, PoPS, causal genes, coding variants, deep vein thrombosis, gene, gene-trait, human, loci, polygenic priority
Author NameAffiliation
Elle M WeeksBroad Institute of MIT and Harvard
Jacob C UlirschBroad Institute of MIT and Harvard
Jacob C UlirschInc.
Jacob C UlirschHarvard Medical School
Nathan Y ChengBroad Institute of MIT and Harvard
Brian L Trippe
Brian L Trippe
Rebecca S FineBroad Institute of MIT and Harvard
Rebecca S FineVertex Pharmaceuticals Incorporated
Rebecca S FineHarvard Medical School
Rebecca S FineDivision of Endocrinology and Center for Basic and Translational Obesity Research, Boston Children's Hospital
Jenkai MiaoBroad Institute of MIT and Harvard
Jenkai MiaoDivision of Endocrinology and Center for Basic and Translational Obesity Research, Boston Children's Hospital
Tejal A PatwardhanBroad Institute of MIT and Harvard
Tejal A PatwardhanHarvard University
Masahiro KanaiBroad Institute of MIT and Harvard
Masahiro KanaiOsaka University Graduate School of Medicine
Masahiro KanaiHarvard Medical School
Masahiro Kanai
Joseph NasserBroad Institute of MIT and Harvard
Charles P FulcoBroad Institute of MIT and Harvard
Charles P Fulco
Katherine C TashmanBroad Institute of MIT and Harvard
François AguetBroad Institute of MIT and Harvard
Taibo LiBroad Institute of MIT and Harvard
Taibo LiJohns Hopkins University School of Medicine
Jose Ordovas-MontanesBroad Institute of MIT and Harvard
Jose Ordovas-MontanesHarvard Stem Cell Institute
Jose Ordovas-MontanesHarvard Medical School
Jose Ordovas-MontanesBoston Children's Hospital
Christopher S SmillieBroad Institute of MIT and Harvard
Christopher S Smillie
Moshe BitonBroad Institute of MIT and Harvard
Moshe BitonWeizmann Institute of Science
Moshe Biton
Alex K ShalekBroad Institute of MIT and Harvard
Alex K ShalekRagon Institute of MGH
Alex K ShalekKoch Institute for Integrative Cancer Research
Alex K Shalek
Alex K ShalekInstitute for Medical Engineering and Science
Alex K ShalekBroad Institute of MIT and Harvard
Alex K ShalekInstitute for Medical Engineering and Science
Alex K Shalek
Alex K ShalekKoch Institute for Integrative Cancer Research
Alex K ShalekRagon Institute of MGH
Ashwin N AnanthakrishnanGastrointestinal Unit and Center for the Study of Inflammatory Bowel Disease
Ramnik J XavierBroad Institute of MIT and Harvard
Ramnik J XavierCenter for Computational and Integrative Biology, Massachusetts General Hospital, Harvard Medical School
Ramnik J XavierGastrointestinal Unit and Center for the Study of Inflammatory Bowel Disease
Ramnik J Xavier
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