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Paper Details

Activation of <i>Notch</i> and <i>Myc</i> Signaling via B-cell-Restricted Depletion of <i>Dnmt3a</i> Generates a Consistent Murine Model of Chronic Lymphocytic Leukemia.
Cancer Res
14
2021
-, Atm, B cell, B cells, B1a cells, CLL, Chronic lymphocytic leukemia, DNA, DNMT3A, Dnmt3a, Dnmt3a-depleted CLL, Ikzf3, MDR, Myc, Myc gene, Notch, Sf3b1, chromosome 15, chronic lymphocytic leukemia, haploinsufficient tumor, high-Myc-expressing CLL cells, human, human CLL samples, methyltransferase DNMT3A, mice, mouse, murine
Author NameAffiliation
Laura Z RassentiMoores Cancer Center, University of California San Diego Health
Thomas J KippsMoores Cancer Center, University of California San Diego Health
Andreas GnirkeBroad Institute of MIT and Harvard
Donna NeubergDana-Farber Cancer Institute, Harvard Medical School
Alexander MeissnerMax Planck Institute for Molecular Genetics
Alexander MeissnerBroad Institute of MIT and Harvard
Alexander MeissnerHarvard University
Catherine J WuDana-Farber Cancer Institute
Catherine J WuHarvard Medical School
Catherine J WuBroad Institute of MIT and Harvard
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