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Paper Details

Structure-guided and phage-assisted evolution of a therapeutic anti-EGFR antibody to reverse acquired resistance.
Nat Commun
8
2022
Ctx, Ctx-, Ctx-VY, EGFR, G465R, amino acid, anti-EGFR antibody, cetuximab, cetuximab epitope, cetuximab variants, colorectal cancers, epidermal growth factor receptor
Author NameAffiliation
James J ChouHarvard Medical School
Tingjun HouInstitute of Drug Metabolism and Pharmaceutical Analysis, College of Pharmaceutical Sciences, Zhejiang University
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Release 1.2