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Paper Details

IRF5 genetic risk variants drive myeloid-specific IRF5 hyperactivation and presymptomatic SLE.
JCI Insight
22
2020
-, B lymphoblastoid cell lines, IFN, IRF5, IRF5 genetic, IRF5 genetic risk variants, IRF5 genetic variants, IRF5 protein, IRF5 transcript, MPO, SLE, SLE immune cells, anti-Ro, circulating plasma cells, interferon regulatory factor 5, interferon regulatory factor 5 (IRF5) locus, myeloid, myeloid compartment, plasmacytoid dendritic cells, risk neutrophils, systemic lupus erythematosus
Author NameAffiliation
Peter K GregersenRobert S. Boas Center for Genomics and Human Genetics, The Feinstein Institutes for Medical Research
Peter S LinsleyBenaroya Research Institute at Virginia Mason
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Release 1.2