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Paper Details

Breast Cancer Risk Genes - Association Analysis in More than 113,000 Women.
N Engl J Med
466
2021
ATM, BARD1, BRCA1, BRCA2, Breast Cancer, CHEK2, ER, ER-negative disease, PALB2, RAD51C, RAD51D, TP53, Women, breast cancer, estrogen, estrogen receptor, protein, protein-truncating variants, putative, susceptibility genes, tumor, women
Author NameAffiliation
Ana OsorioUniversity of Cambridge, MRC Institute of Genetics and Molecular Medicine (A. Campbell, University of Edinburgh, University of Edinburgh Medical School (A. Campbell, Health Services Research, University of Manchester, the NIHR Manchester Biomedical Research Unit (E.F.H.) and the Nightingale Breast Screening Centre, Wythenshawe Hospital (E.F.H., St. Mary's Hospital, Manchester University NHS Foundation Trust (W.G.N., the School of Cancer and Pharmaceutical Sciences, Comprehensive Cancer Centre, King's College London, the Institute of Cancer and Genomic Sciences, University of Birmingham, and the Wellcome Trust Centre for Human Genetics and Oxford NIHR Biomedical Research Centre, University of Oxford, Spanish National Cancer Research Center, Hospital Universitario La Paz (M.P.Z.), Hospital Clinico San Carlos, Instituto de Investigacion Sanitaria del Hospital Clinico San Carlos (M. de la Hoya), Galician Foundation of Genomic Medicine, Instituto de Investigacion Sanitaria de Santiago de Co
Sabine BehrensUniversity of Cambridge, MRC Institute of Genetics and Molecular Medicine (A. Campbell, University of Edinburgh, University of Edinburgh Medical School (A. Campbell, Health Services Research, University of Manchester, the NIHR Manchester Biomedical Research Unit (E.F.H.) and the Nightingale Breast Screening Centre, Wythenshawe Hospital (E.F.H., St. Mary's Hospital, Manchester University NHS Foundation Trust (W.G.N., the School of Cancer and Pharmaceutical Sciences, Comprehensive Cancer Centre, King's College London, the Institute of Cancer and Genomic Sciences, University of Birmingham, and the Wellcome Trust Centre for Human Genetics and Oxford NIHR Biomedical Research Centre, University of Oxford, Spanish National Cancer Research Center, Hospital Universitario La Paz (M.P.Z.), Hospital Clinico San Carlos, Instituto de Investigacion Sanitaria del Hospital Clinico San Carlos (M. de la Hoya), Galician Foundation of Genomic Medicine, Instituto de Investigacion Sanitaria de Santiago de Co
Anne-Lise B??rresen-DaleUniversity of Cambridge, MRC Institute of Genetics and Molecular Medicine (A. Campbell, University of Edinburgh, University of Edinburgh Medical School (A. Campbell, Health Services Research, University of Manchester, the NIHR Manchester Biomedical Research Unit (E.F.H.) and the Nightingale Breast Screening Centre, Wythenshawe Hospital (E.F.H., St. Mary's Hospital, Manchester University NHS Foundation Trust (W.G.N., the School of Cancer and Pharmaceutical Sciences, Comprehensive Cancer Centre, King's College London, the Institute of Cancer and Genomic Sciences, University of Birmingham, and the Wellcome Trust Centre for Human Genetics and Oxford NIHR Biomedical Research Centre, University of Oxford, Spanish National Cancer Research Center, Hospital Universitario La Paz (M.P.Z.), Hospital Clinico San Carlos, Instituto de Investigacion Sanitaria del Hospital Clinico San Carlos (M. de la Hoya), Galician Foundation of Genomic Medicine, Instituto de Investigacion Sanitaria de Santiago de Co
Anne-Lise B??rresen-DaleUniversity of Cambridge, MRC Institute of Genetics and Molecular Medicine (A. Campbell, University of Edinburgh, University of Edinburgh Medical School (A. Campbell, Health Services Research, University of Manchester, the NIHR Manchester Biomedical Research Unit (E.F.H.) and the Nightingale Breast Screening Centre, Wythenshawe Hospital (E.F.H., St. Mary's Hospital, Manchester University NHS Foundation Trust (W.G.N., the School of Cancer and Pharmaceutical Sciences, Comprehensive Cancer Centre, King's College London, the Institute of Cancer and Genomic Sciences, University of Birmingham, and the Wellcome Trust Centre for Human Genetics and Oxford NIHR Biomedical Research Centre, University of Oxford, Spanish National Cancer Research Center, Hospital Universitario La Paz (M.P.Z.), Hospital Clinico San Carlos, Instituto de Investigacion Sanitaria del Hospital Clinico San Carlos (M. de la Hoya), Galician Foundation of Genomic Medicine, Instituto de Investigacion Sanitaria de Santiago de Co
Angel CarracedoUniversity of Cambridge, MRC Institute of Genetics and Molecular Medicine (A. Campbell, University of Edinburgh, University of Edinburgh Medical School (A. Campbell, Health Services Research, University of Manchester, the NIHR Manchester Biomedical Research Unit (E.F.H.) and the Nightingale Breast Screening Centre, Wythenshawe Hospital (E.F.H., St. Mary's Hospital, Manchester University NHS Foundation Trust (W.G.N., the School of Cancer and Pharmaceutical Sciences, Comprehensive Cancer Centre, King's College London, the Institute of Cancer and Genomic Sciences, University of Birmingham, and the Wellcome Trust Centre for Human Genetics and Oxford NIHR Biomedical Research Centre, University of Oxford, Spanish National Cancer Research Center, Hospital Universitario La Paz (M.P.Z.), Hospital Clinico San Carlos, Instituto de Investigacion Sanitaria del Hospital Clinico San Carlos (M. de la Hoya), Galician Foundation of Genomic Medicine, Instituto de Investigacion Sanitaria de Santiago de Co
Melissa H CessnaUniversity of Cambridge, MRC Institute of Genetics and Molecular Medicine (A. Campbell, University of Edinburgh, University of Edinburgh Medical School (A. Campbell, Health Services Research, University of Manchester, the NIHR Manchester Biomedical Research Unit (E.F.H.) and the Nightingale Breast Screening Centre, Wythenshawe Hospital (E.F.H., St. Mary's Hospital, Manchester University NHS Foundation Trust (W.G.N., the School of Cancer and Pharmaceutical Sciences, Comprehensive Cancer Centre, King's College London, the Institute of Cancer and Genomic Sciences, University of Birmingham, and the Wellcome Trust Centre for Human Genetics and Oxford NIHR Biomedical Research Centre, University of Oxford, Spanish National Cancer Research Center, Hospital Universitario La Paz (M.P.Z.), Hospital Clinico San Carlos, Instituto de Investigacion Sanitaria del Hospital Clinico San Carlos (M. de la Hoya), Galician Foundation of Genomic Medicine, Instituto de Investigacion Sanitaria de Santiago de Co
Stephen J ChanockUniversity of Cambridge, MRC Institute of Genetics and Molecular Medicine (A. Campbell, University of Edinburgh, University of Edinburgh Medical School (A. Campbell, Health Services Research, University of Manchester, the NIHR Manchester Biomedical Research Unit (E.F.H.) and the Nightingale Breast Screening Centre, Wythenshawe Hospital (E.F.H., St. Mary's Hospital, Manchester University NHS Foundation Trust (W.G.N., the School of Cancer and Pharmaceutical Sciences, Comprehensive Cancer Centre, King's College London, the Institute of Cancer and Genomic Sciences, University of Birmingham, and the Wellcome Trust Centre for Human Genetics and Oxford NIHR Biomedical Research Centre, University of Oxford, Spanish National Cancer Research Center, Hospital Universitario La Paz (M.P.Z.), Hospital Clinico San Carlos, Instituto de Investigacion Sanitaria del Hospital Clinico San Carlos (M. de la Hoya), Galician Foundation of Genomic Medicine, Instituto de Investigacion Sanitaria de Santiago de Co
Stephen J ChanockUniversity of Cambridge, MRC Institute of Genetics and Molecular Medicine (A. Campbell, University of Edinburgh, University of Edinburgh Medical School (A. Campbell, Health Services Research, University of Manchester, the NIHR Manchester Biomedical Research Unit (E.F.H.) and the Nightingale Breast Screening Centre, Wythenshawe Hospital (E.F.H., St. Mary's Hospital, Manchester University NHS Foundation Trust (W.G.N., the School of Cancer and Pharmaceutical Sciences, Comprehensive Cancer Centre, King's College London, the Institute of Cancer and Genomic Sciences, University of Birmingham, and the Wellcome Trust Centre for Human Genetics and Oxford NIHR Biomedical Research Centre, University of Oxford, Spanish National Cancer Research Center, Hospital Universitario La Paz (M.P.Z.), Hospital Clinico San Carlos, Instituto de Investigacion Sanitaria del Hospital Clinico San Carlos (M. de la Hoya), Galician Foundation of Genomic Medicine, Instituto de Investigacion Sanitaria de Santiago de Co
Peter A FaschingUniversity of Cambridge, MRC Institute of Genetics and Molecular Medicine (A. Campbell, University of Edinburgh, University of Edinburgh Medical School (A. Campbell, Health Services Research, University of Manchester, the NIHR Manchester Biomedical Research Unit (E.F.H.) and the Nightingale Breast Screening Centre, Wythenshawe Hospital (E.F.H., St. Mary's Hospital, Manchester University NHS Foundation Trust (W.G.N., the School of Cancer and Pharmaceutical Sciences, Comprehensive Cancer Centre, King's College London, the Institute of Cancer and Genomic Sciences, University of Birmingham, and the Wellcome Trust Centre for Human Genetics and Oxford NIHR Biomedical Research Centre, University of Oxford, Spanish National Cancer Research Center, Hospital Universitario La Paz (M.P.Z.), Hospital Clinico San Carlos, Instituto de Investigacion Sanitaria del Hospital Clinico San Carlos (M. de la Hoya), Galician Foundation of Genomic Medicine, Instituto de Investigacion Sanitaria de Santiago de Co
Jonine D FigueroaUniversity of Cambridge, MRC Institute of Genetics and Molecular Medicine (A. Campbell, University of Edinburgh, University of Edinburgh Medical School (A. Campbell, Health Services Research, University of Manchester, the NIHR Manchester Biomedical Research Unit (E.F.H.) and the Nightingale Breast Screening Centre, Wythenshawe Hospital (E.F.H., St. Mary's Hospital, Manchester University NHS Foundation Trust (W.G.N., the School of Cancer and Pharmaceutical Sciences, Comprehensive Cancer Centre, King's College London, the Institute of Cancer and Genomic Sciences, University of Birmingham, and the Wellcome Trust Centre for Human Genetics and Oxford NIHR Biomedical Research Centre, University of Oxford, Spanish National Cancer Research Center, Hospital Universitario La Paz (M.P.Z.), Hospital Clinico San Carlos, Instituto de Investigacion Sanitaria del Hospital Clinico San Carlos (M. de la Hoya), Galician Foundation of Genomic Medicine, Instituto de Investigacion Sanitaria de Santiago de Co
Jonine D FigueroaUniversity of Cambridge, MRC Institute of Genetics and Molecular Medicine (A. Campbell, University of Edinburgh, University of Edinburgh Medical School (A. Campbell, Health Services Research, University of Manchester, the NIHR Manchester Biomedical Research Unit (E.F.H.) and the Nightingale Breast Screening Centre, Wythenshawe Hospital (E.F.H., St. Mary's Hospital, Manchester University NHS Foundation Trust (W.G.N., the School of Cancer and Pharmaceutical Sciences, Comprehensive Cancer Centre, King's College London, the Institute of Cancer and Genomic Sciences, University of Birmingham, and the Wellcome Trust Centre for Human Genetics and Oxford NIHR Biomedical Research Centre, University of Oxford, Spanish National Cancer Research Center, Hospital Universitario La Paz (M.P.Z.), Hospital Clinico San Carlos, Instituto de Investigacion Sanitaria del Hospital Clinico San Carlos (M. de la Hoya), Galician Foundation of Genomic Medicine, Instituto de Investigacion Sanitaria de Santiago de Co
Graham G GilesUniversity of Cambridge, MRC Institute of Genetics and Molecular Medicine (A. Campbell, University of Edinburgh, University of Edinburgh Medical School (A. Campbell, Health Services Research, University of Manchester, the NIHR Manchester Biomedical Research Unit (E.F.H.) and the Nightingale Breast Screening Centre, Wythenshawe Hospital (E.F.H., St. Mary's Hospital, Manchester University NHS Foundation Trust (W.G.N., the School of Cancer and Pharmaceutical Sciences, Comprehensive Cancer Centre, King's College London, the Institute of Cancer and Genomic Sciences, University of Birmingham, and the Wellcome Trust Centre for Human Genetics and Oxford NIHR Biomedical Research Centre, University of Oxford, Spanish National Cancer Research Center, Hospital Universitario La Paz (M.P.Z.), Hospital Clinico San Carlos, Instituto de Investigacion Sanitaria del Hospital Clinico San Carlos (M. de la Hoya), Galician Foundation of Genomic Medicine, Instituto de Investigacion Sanitaria de Santiago de Co
Per HallUniversity of Cambridge, MRC Institute of Genetics and Molecular Medicine (A. Campbell, University of Edinburgh, University of Edinburgh Medical School (A. Campbell, Health Services Research, University of Manchester, the NIHR Manchester Biomedical Research Unit (E.F.H.) and the Nightingale Breast Screening Centre, Wythenshawe Hospital (E.F.H., St. Mary's Hospital, Manchester University NHS Foundation Trust (W.G.N., the School of Cancer and Pharmaceutical Sciences, Comprehensive Cancer Centre, King's College London, the Institute of Cancer and Genomic Sciences, University of Birmingham, and the Wellcome Trust Centre for Human Genetics and Oxford NIHR Biomedical Research Centre, University of Oxford, Spanish National Cancer Research Center, Hospital Universitario La Paz (M.P.Z.), Hospital Clinico San Carlos, Instituto de Investigacion Sanitaria del Hospital Clinico San Carlos (M. de la Hoya), Galician Foundation of Genomic Medicine, Instituto de Investigacion Sanitaria de Santiago de Co
Vessela N KristensenUniversity of Cambridge, MRC Institute of Genetics and Molecular Medicine (A. Campbell, University of Edinburgh, University of Edinburgh Medical School (A. Campbell, Health Services Research, University of Manchester, the NIHR Manchester Biomedical Research Unit (E.F.H.) and the Nightingale Breast Screening Centre, Wythenshawe Hospital (E.F.H., St. Mary's Hospital, Manchester University NHS Foundation Trust (W.G.N., the School of Cancer and Pharmaceutical Sciences, Comprehensive Cancer Centre, King's College London, the Institute of Cancer and Genomic Sciences, University of Birmingham, and the Wellcome Trust Centre for Human Genetics and Oxford NIHR Biomedical Research Centre, University of Oxford, Spanish National Cancer Research Center, Hospital Universitario La Paz (M.P.Z.), Hospital Clinico San Carlos, Instituto de Investigacion Sanitaria del Hospital Clinico San Carlos (M. de la Hoya), Galician Foundation of Genomic Medicine, Instituto de Investigacion Sanitaria de Santiago de Co
Jeong-Won LeeUniversity of Cambridge, MRC Institute of Genetics and Molecular Medicine (A. Campbell, University of Edinburgh, University of Edinburgh Medical School (A. Campbell, Health Services Research, University of Manchester, the NIHR Manchester Biomedical Research Unit (E.F.H.) and the Nightingale Breast Screening Centre, Wythenshawe Hospital (E.F.H., St. Mary's Hospital, Manchester University NHS Foundation Trust (W.G.N., the School of Cancer and Pharmaceutical Sciences, Comprehensive Cancer Centre, King's College London, the Institute of Cancer and Genomic Sciences, University of Birmingham, and the Wellcome Trust Centre for Human Genetics and Oxford NIHR Biomedical Research Centre, University of Oxford, Spanish National Cancer Research Center, Hospital Universitario La Paz (M.P.Z.), Hospital Clinico San Carlos, Instituto de Investigacion Sanitaria del Hospital Clinico San Carlos (M. de la Hoya), Galician Foundation of Genomic Medicine, Instituto de Investigacion Sanitaria de Santiago de Co
Jan LubinskiUniversity of Cambridge, MRC Institute of Genetics and Molecular Medicine (A. Campbell, University of Edinburgh, University of Edinburgh Medical School (A. Campbell, Health Services Research, University of Manchester, the NIHR Manchester Biomedical Research Unit (E.F.H.) and the Nightingale Breast Screening Centre, Wythenshawe Hospital (E.F.H., St. Mary's Hospital, Manchester University NHS Foundation Trust (W.G.N., the School of Cancer and Pharmaceutical Sciences, Comprehensive Cancer Centre, King's College London, the Institute of Cancer and Genomic Sciences, University of Birmingham, and the Wellcome Trust Centre for Human Genetics and Oxford NIHR Biomedical Research Centre, University of Oxford, Spanish National Cancer Research Center, Hospital Universitario La Paz (M.P.Z.), Hospital Clinico San Carlos, Instituto de Investigacion Sanitaria del Hospital Clinico San Carlos (M. de la Hoya), Galician Foundation of Genomic Medicine, Instituto de Investigacion Sanitaria de Santiago de Co
Jan LubinskiUniversity of Cambridge, MRC Institute of Genetics and Molecular Medicine (A. Campbell, University of Edinburgh, University of Edinburgh Medical School (A. Campbell, Health Services Research, University of Manchester, the NIHR Manchester Biomedical Research Unit (E.F.H.) and the Nightingale Breast Screening Centre, Wythenshawe Hospital (E.F.H., St. Mary's Hospital, Manchester University NHS Foundation Trust (W.G.N., the School of Cancer and Pharmaceutical Sciences, Comprehensive Cancer Centre, King's College London, the Institute of Cancer and Genomic Sciences, University of Birmingham, and the Wellcome Trust Centre for Human Genetics and Oxford NIHR Biomedical Research Centre, University of Oxford, Spanish National Cancer Research Center, Hospital Universitario La Paz (M.P.Z.), Hospital Clinico San Carlos, Instituto de Investigacion Sanitaria del Hospital Clinico San Carlos (M. de la Hoya), Galician Foundation of Genomic Medicine, Instituto de Investigacion Sanitaria de Santiago de Co
Siranoush ManoukianUniversity of Cambridge, MRC Institute of Genetics and Molecular Medicine (A. Campbell, University of Edinburgh, University of Edinburgh Medical School (A. Campbell, Health Services Research, University of Manchester, the NIHR Manchester Biomedical Research Unit (E.F.H.) and the Nightingale Breast Screening Centre, Wythenshawe Hospital (E.F.H., St. Mary's Hospital, Manchester University NHS Foundation Trust (W.G.N., the School of Cancer and Pharmaceutical Sciences, Comprehensive Cancer Centre, King's College London, the Institute of Cancer and Genomic Sciences, University of Birmingham, and the Wellcome Trust Centre for Human Genetics and Oxford NIHR Biomedical Research Centre, University of Oxford, Spanish National Cancer Research Center, Hospital Universitario La Paz (M.P.Z.), Hospital Clinico San Carlos, Instituto de Investigacion Sanitaria del Hospital Clinico San Carlos (M. de la Hoya), Galician Foundation of Genomic Medicine, Instituto de Investigacion Sanitaria de Santiago de Co
Maria Elena MartinezUniversity of Cambridge, MRC Institute of Genetics and Molecular Medicine (A. Campbell, University of Edinburgh, University of Edinburgh Medical School (A. Campbell, Health Services Research, University of Manchester, the NIHR Manchester Biomedical Research Unit (E.F.H.) and the Nightingale Breast Screening Centre, Wythenshawe Hospital (E.F.H., St. Mary's Hospital, Manchester University NHS Foundation Trust (W.G.N., the School of Cancer and Pharmaceutical Sciences, Comprehensive Cancer Centre, King's College London, the Institute of Cancer and Genomic Sciences, University of Birmingham, and the Wellcome Trust Centre for Human Genetics and Oxford NIHR Biomedical Research Centre, University of Oxford, Spanish National Cancer Research Center, Hospital Universitario La Paz (M.P.Z.), Hospital Clinico San Carlos, Instituto de Investigacion Sanitaria del Hospital Clinico San Carlos (M. de la Hoya), Galician Foundation of Genomic Medicine, Instituto de Investigacion Sanitaria de Santiago de Co
Børge G NordestgaardUniversity of Cambridge, MRC Institute of Genetics and Molecular Medicine (A. Campbell, University of Edinburgh, University of Edinburgh Medical School (A. Campbell, Health Services Research, University of Manchester, the NIHR Manchester Biomedical Research Unit (E.F.H.) and the Nightingale Breast Screening Centre, Wythenshawe Hospital (E.F.H., St. Mary's Hospital, Manchester University NHS Foundation Trust (W.G.N., the School of Cancer and Pharmaceutical Sciences, Comprehensive Cancer Centre, King's College London, the Institute of Cancer and Genomic Sciences, University of Birmingham, and the Wellcome Trust Centre for Human Genetics and Oxford NIHR Biomedical Research Centre, University of Oxford, Spanish National Cancer Research Center, Hospital Universitario La Paz (M.P.Z.), Hospital Clinico San Carlos, Instituto de Investigacion Sanitaria del Hospital Clinico San Carlos (M. de la Hoya), Galician Foundation of Genomic Medicine, Instituto de Investigacion Sanitaria de Santiago de Co
Paolo RadiceUniversity of Cambridge, MRC Institute of Genetics and Molecular Medicine (A. Campbell, University of Edinburgh, University of Edinburgh Medical School (A. Campbell, Health Services Research, University of Manchester, the NIHR Manchester Biomedical Research Unit (E.F.H.) and the Nightingale Breast Screening Centre, Wythenshawe Hospital (E.F.H., St. Mary's Hospital, Manchester University NHS Foundation Trust (W.G.N., the School of Cancer and Pharmaceutical Sciences, Comprehensive Cancer Centre, King's College London, the Institute of Cancer and Genomic Sciences, University of Birmingham, and the Wellcome Trust Centre for Human Genetics and Oxford NIHR Biomedical Research Centre, University of Oxford, Spanish National Cancer Research Center, Hospital Universitario La Paz (M.P.Z.), Hospital Clinico San Carlos, Instituto de Investigacion Sanitaria del Hospital Clinico San Carlos (M. de la Hoya), Galician Foundation of Genomic Medicine, Instituto de Investigacion Sanitaria de Santiago de Co
Valerie RheniusUniversity of Cambridge, MRC Institute of Genetics and Molecular Medicine (A. Campbell, University of Edinburgh, University of Edinburgh Medical School (A. Campbell, Health Services Research, University of Manchester, the NIHR Manchester Biomedical Research Unit (E.F.H.) and the Nightingale Breast Screening Centre, Wythenshawe Hospital (E.F.H., St. Mary's Hospital, Manchester University NHS Foundation Trust (W.G.N., the School of Cancer and Pharmaceutical Sciences, Comprehensive Cancer Centre, King's College London, the Institute of Cancer and Genomic Sciences, University of Birmingham, and the Wellcome Trust Centre for Human Genetics and Oxford NIHR Biomedical Research Centre, University of Oxford, Spanish National Cancer Research Center, Hospital Universitario La Paz (M.P.Z.), Hospital Clinico San Carlos, Instituto de Investigacion Sanitaria del Hospital Clinico San Carlos (M. de la Hoya), Galician Foundation of Genomic Medicine, Instituto de Investigacion Sanitaria de Santiago de Co
Christi J van AsperenUniversity of Cambridge, MRC Institute of Genetics and Molecular Medicine (A. Campbell, University of Edinburgh, University of Edinburgh Medical School (A. Campbell, Health Services Research, University of Manchester, the NIHR Manchester Biomedical Research Unit (E.F.H.) and the Nightingale Breast Screening Centre, Wythenshawe Hospital (E.F.H., St. Mary's Hospital, Manchester University NHS Foundation Trust (W.G.N., the School of Cancer and Pharmaceutical Sciences, Comprehensive Cancer Centre, King's College London, the Institute of Cancer and Genomic Sciences, University of Birmingham, and the Wellcome Trust Centre for Human Genetics and Oxford NIHR Biomedical Research Centre, University of Oxford, Spanish National Cancer Research Center, Hospital Universitario La Paz (M.P.Z.), Hospital Clinico San Carlos, Instituto de Investigacion Sanitaria del Hospital Clinico San Carlos (M. de la Hoya), Galician Foundation of Genomic Medicine, Instituto de Investigacion Sanitaria de Santiago de Co
Rob M van DamUniversity of Cambridge, MRC Institute of Genetics and Molecular Medicine (A. Campbell, University of Edinburgh, University of Edinburgh Medical School (A. Campbell, Health Services Research, University of Manchester, the NIHR Manchester Biomedical Research Unit (E.F.H.) and the Nightingale Breast Screening Centre, Wythenshawe Hospital (E.F.H., St. Mary's Hospital, Manchester University NHS Foundation Trust (W.G.N., the School of Cancer and Pharmaceutical Sciences, Comprehensive Cancer Centre, King's College London, the Institute of Cancer and Genomic Sciences, University of Birmingham, and the Wellcome Trust Centre for Human Genetics and Oxford NIHR Biomedical Research Centre, University of Oxford, Spanish National Cancer Research Center, Hospital Universitario La Paz (M.P.Z.), Hospital Clinico San Carlos, Instituto de Investigacion Sanitaria del Hospital Clinico San Carlos (M. de la Hoya), Galician Foundation of Genomic Medicine, Instituto de Investigacion Sanitaria de Santiago de Co
Xiaohong R YangUniversity of Cambridge, MRC Institute of Genetics and Molecular Medicine (A. Campbell, University of Edinburgh, University of Edinburgh Medical School (A. Campbell, Health Services Research, University of Manchester, the NIHR Manchester Biomedical Research Unit (E.F.H.) and the Nightingale Breast Screening Centre, Wythenshawe Hospital (E.F.H., St. Mary's Hospital, Manchester University NHS Foundation Trust (W.G.N., the School of Cancer and Pharmaceutical Sciences, Comprehensive Cancer Centre, King's College London, the Institute of Cancer and Genomic Sciences, University of Birmingham, and the Wellcome Trust Centre for Human Genetics and Oxford NIHR Biomedical Research Centre, University of Oxford, Spanish National Cancer Research Center, Hospital Universitario La Paz (M.P.Z.), Hospital Clinico San Carlos, Instituto de Investigacion Sanitaria del Hospital Clinico San Carlos (M. de la Hoya), Galician Foundation of Genomic Medicine, Instituto de Investigacion Sanitaria de Santiago de Co
Xiaohong R YangUniversity of Cambridge, MRC Institute of Genetics and Molecular Medicine (A. Campbell, University of Edinburgh, University of Edinburgh Medical School (A. Campbell, Health Services Research, University of Manchester, the NIHR Manchester Biomedical Research Unit (E.F.H.) and the Nightingale Breast Screening Centre, Wythenshawe Hospital (E.F.H., St. Mary's Hospital, Manchester University NHS Foundation Trust (W.G.N., the School of Cancer and Pharmaceutical Sciences, Comprehensive Cancer Centre, King's College London, the Institute of Cancer and Genomic Sciences, University of Birmingham, and the Wellcome Trust Centre for Human Genetics and Oxford NIHR Biomedical Research Centre, University of Oxford, Spanish National Cancer Research Center, Hospital Universitario La Paz (M.P.Z.), Hospital Clinico San Carlos, Instituto de Investigacion Sanitaria del Hospital Clinico San Carlos (M. de la Hoya), Galician Foundation of Genomic Medicine, Instituto de Investigacion Sanitaria de Santiago de Co
Irene L AndrulisUniversity of Cambridge, MRC Institute of Genetics and Molecular Medicine (A. Campbell, University of Edinburgh, University of Edinburgh Medical School (A. Campbell, Health Services Research, University of Manchester, the NIHR Manchester Biomedical Research Unit (E.F.H.) and the Nightingale Breast Screening Centre, Wythenshawe Hospital (E.F.H., St. Mary's Hospital, Manchester University NHS Foundation Trust (W.G.N., the School of Cancer and Pharmaceutical Sciences, Comprehensive Cancer Centre, King's College London, the Institute of Cancer and Genomic Sciences, University of Birmingham, and the Wellcome Trust Centre for Human Genetics and Oxford NIHR Biomedical Research Centre, University of Oxford, Spanish National Cancer Research Center, Hospital Universitario La Paz (M.P.Z.), Hospital Clinico San Carlos, Instituto de Investigacion Sanitaria del Hospital Clinico San Carlos (M. de la Hoya), Galician Foundation of Genomic Medicine, Instituto de Investigacion Sanitaria de Santiago de Co
Irene L AndrulisUniversity of Cambridge, MRC Institute of Genetics and Molecular Medicine (A. Campbell, University of Edinburgh, University of Edinburgh Medical School (A. Campbell, Health Services Research, University of Manchester, the NIHR Manchester Biomedical Research Unit (E.F.H.) and the Nightingale Breast Screening Centre, Wythenshawe Hospital (E.F.H., St. Mary's Hospital, Manchester University NHS Foundation Trust (W.G.N., the School of Cancer and Pharmaceutical Sciences, Comprehensive Cancer Centre, King's College London, the Institute of Cancer and Genomic Sciences, University of Birmingham, and the Wellcome Trust Centre for Human Genetics and Oxford NIHR Biomedical Research Centre, University of Oxford, Spanish National Cancer Research Center, Hospital Universitario La Paz (M.P.Z.), Hospital Clinico San Carlos, Instituto de Investigacion Sanitaria del Hospital Clinico San Carlos (M. de la Hoya), Galician Foundation of Genomic Medicine, Instituto de Investigacion Sanitaria de Santiago de Co
Jenny Chang-ClaudeUniversity of Cambridge, MRC Institute of Genetics and Molecular Medicine (A. Campbell, University of Edinburgh, University of Edinburgh Medical School (A. Campbell, Health Services Research, University of Manchester, the NIHR Manchester Biomedical Research Unit (E.F.H.) and the Nightingale Breast Screening Centre, Wythenshawe Hospital (E.F.H., St. Mary's Hospital, Manchester University NHS Foundation Trust (W.G.N., the School of Cancer and Pharmaceutical Sciences, Comprehensive Cancer Centre, King's College London, the Institute of Cancer and Genomic Sciences, University of Birmingham, and the Wellcome Trust Centre for Human Genetics and Oxford NIHR Biomedical Research Centre, University of Oxford, Spanish National Cancer Research Center, Hospital Universitario La Paz (M.P.Z.), Hospital Clinico San Carlos, Instituto de Investigacion Sanitaria del Hospital Clinico San Carlos (M. de la Hoya), Galician Foundation of Genomic Medicine, Instituto de Investigacion Sanitaria de Santiago de Co
Montserrat Garcia-ClosasUniversity of Cambridge, MRC Institute of Genetics and Molecular Medicine (A. Campbell, University of Edinburgh, University of Edinburgh Medical School (A. Campbell, Health Services Research, University of Manchester, the NIHR Manchester Biomedical Research Unit (E.F.H.) and the Nightingale Breast Screening Centre, Wythenshawe Hospital (E.F.H., St. Mary's Hospital, Manchester University NHS Foundation Trust (W.G.N., the School of Cancer and Pharmaceutical Sciences, Comprehensive Cancer Centre, King's College London, the Institute of Cancer and Genomic Sciences, University of Birmingham, and the Wellcome Trust Centre for Human Genetics and Oxford NIHR Biomedical Research Centre, University of Oxford, Spanish National Cancer Research Center, Hospital Universitario La Paz (M.P.Z.), Hospital Clinico San Carlos, Instituto de Investigacion Sanitaria del Hospital Clinico San Carlos (M. de la Hoya), Galician Foundation of Genomic Medicine, Instituto de Investigacion Sanitaria de Santiago de Co
Montserrat Garcia-ClosasUniversity of Cambridge, MRC Institute of Genetics and Molecular Medicine (A. Campbell, University of Edinburgh, University of Edinburgh Medical School (A. Campbell, Health Services Research, University of Manchester, the NIHR Manchester Biomedical Research Unit (E.F.H.) and the Nightingale Breast Screening Centre, Wythenshawe Hospital (E.F.H., St. Mary's Hospital, Manchester University NHS Foundation Trust (W.G.N., the School of Cancer and Pharmaceutical Sciences, Comprehensive Cancer Centre, King's College London, the Institute of Cancer and Genomic Sciences, University of Birmingham, and the Wellcome Trust Centre for Human Genetics and Oxford NIHR Biomedical Research Centre, University of Oxford, Spanish National Cancer Research Center, Hospital Universitario La Paz (M.P.Z.), Hospital Clinico San Carlos, Instituto de Investigacion Sanitaria del Hospital Clinico San Carlos (M. de la Hoya), Galician Foundation of Genomic Medicine, Instituto de Investigacion Sanitaria de Santiago de Co
Georgia Chenevix-TrenchUniversity of Cambridge, MRC Institute of Genetics and Molecular Medicine (A. Campbell, University of Edinburgh, University of Edinburgh Medical School (A. Campbell, Health Services Research, University of Manchester, the NIHR Manchester Biomedical Research Unit (E.F.H.) and the Nightingale Breast Screening Centre, Wythenshawe Hospital (E.F.H., St. Mary's Hospital, Manchester University NHS Foundation Trust (W.G.N., the School of Cancer and Pharmaceutical Sciences, Comprehensive Cancer Centre, King's College London, the Institute of Cancer and Genomic Sciences, University of Birmingham, and the Wellcome Trust Centre for Human Genetics and Oxford NIHR Biomedical Research Centre, University of Oxford, Spanish National Cancer Research Center, Hospital Universitario La Paz (M.P.Z.), Hospital Clinico San Carlos, Instituto de Investigacion Sanitaria del Hospital Clinico San Carlos (M. de la Hoya), Galician Foundation of Genomic Medicine, Instituto de Investigacion Sanitaria de Santiago de Co
Georgia Chenevix-TrenchUniversity of Cambridge, MRC Institute of Genetics and Molecular Medicine (A. Campbell, University of Edinburgh, University of Edinburgh Medical School (A. Campbell, Health Services Research, University of Manchester, the NIHR Manchester Biomedical Research Unit (E.F.H.) and the Nightingale Breast Screening Centre, Wythenshawe Hospital (E.F.H., St. Mary's Hospital, Manchester University NHS Foundation Trust (W.G.N., the School of Cancer and Pharmaceutical Sciences, Comprehensive Cancer Centre, King's College London, the Institute of Cancer and Genomic Sciences, University of Birmingham, and the Wellcome Trust Centre for Human Genetics and Oxford NIHR Biomedical Research Centre, University of Oxford, Spanish National Cancer Research Center, Hospital Universitario La Paz (M.P.Z.), Hospital Clinico San Carlos, Instituto de Investigacion Sanitaria del Hospital Clinico San Carlos (M. de la Hoya), Galician Foundation of Genomic Medicine, Instituto de Investigacion Sanitaria de Santiago de Co
Roger L MilneUniversity of Cambridge, MRC Institute of Genetics and Molecular Medicine (A. Campbell, University of Edinburgh, University of Edinburgh Medical School (A. Campbell, Health Services Research, University of Manchester, the NIHR Manchester Biomedical Research Unit (E.F.H.) and the Nightingale Breast Screening Centre, Wythenshawe Hospital (E.F.H., St. Mary's Hospital, Manchester University NHS Foundation Trust (W.G.N., the School of Cancer and Pharmaceutical Sciences, Comprehensive Cancer Centre, King's College London, the Institute of Cancer and Genomic Sciences, University of Birmingham, and the Wellcome Trust Centre for Human Genetics and Oxford NIHR Biomedical Research Centre, University of Oxford, Spanish National Cancer Research Center, Hospital Universitario La Paz (M.P.Z.), Hospital Clinico San Carlos, Instituto de Investigacion Sanitaria del Hospital Clinico San Carlos (M. de la Hoya), Galician Foundation of Genomic Medicine, Instituto de Investigacion Sanitaria de Santiago de Co
Paul D P PharoahUniversity of Cambridge, MRC Institute of Genetics and Molecular Medicine (A. Campbell, University of Edinburgh, University of Edinburgh Medical School (A. Campbell, Health Services Research, University of Manchester, the NIHR Manchester Biomedical Research Unit (E.F.H.) and the Nightingale Breast Screening Centre, Wythenshawe Hospital (E.F.H., St. Mary's Hospital, Manchester University NHS Foundation Trust (W.G.N., the School of Cancer and Pharmaceutical Sciences, Comprehensive Cancer Centre, King's College London, the Institute of Cancer and Genomic Sciences, University of Birmingham, and the Wellcome Trust Centre for Human Genetics and Oxford NIHR Biomedical Research Centre, University of Oxford, Spanish National Cancer Research Center, Hospital Universitario La Paz (M.P.Z.), Hospital Clinico San Carlos, Instituto de Investigacion Sanitaria del Hospital Clinico San Carlos (M. de la Hoya), Galician Foundation of Genomic Medicine, Instituto de Investigacion Sanitaria de Santiago de Co
Paul D P PharoahUniversity of Cambridge, MRC Institute of Genetics and Molecular Medicine (A. Campbell, University of Edinburgh, University of Edinburgh Medical School (A. Campbell, Health Services Research, University of Manchester, the NIHR Manchester Biomedical Research Unit (E.F.H.) and the Nightingale Breast Screening Centre, Wythenshawe Hospital (E.F.H., St. Mary's Hospital, Manchester University NHS Foundation Trust (W.G.N., the School of Cancer and Pharmaceutical Sciences, Comprehensive Cancer Centre, King's College London, the Institute of Cancer and Genomic Sciences, University of Birmingham, and the Wellcome Trust Centre for Human Genetics and Oxford NIHR Biomedical Research Centre, University of Oxford, Spanish National Cancer Research Center, Hospital Universitario La Paz (M.P.Z.), Hospital Clinico San Carlos, Instituto de Investigacion Sanitaria del Hospital Clinico San Carlos (M. de la Hoya), Galician Foundation of Genomic Medicine, Instituto de Investigacion Sanitaria de Santiago de Co
Georgia Chenevix-TrenchUniversity of Cambridge, MRC Institute of Genetics and Molecular Medicine (A. Campbell, University of Edinburgh, University of Edinburgh Medical School (A. Campbell, Health Services Research, University of Manchester, the NIHR Manchester Biomedical Research Unit (E.F.H.) and the Nightingale Breast Screening Centre, Wythenshawe Hospital (E.F.H., St. Mary's Hospital, Manchester University NHS Foundation Trust (W.G.N., the School of Cancer and Pharmaceutical Sciences, Comprehensive Cancer Centre, King's College London, the Institute of Cancer and Genomic Sciences, University of Birmingham, and the Wellcome Trust Centre for Human Genetics and Oxford NIHR Biomedical Research Centre, University of Oxford, Spanish National Cancer Research Center, Hospital Universitario La Paz (M.P.Z.), Hospital Clinico San Carlos, Instituto de Investigacion Sanitaria del Hospital Clinico San Carlos (M. de la Hoya), Galician Foundation of Genomic Medicine, Instituto de Investigacion Sanitaria de Santiago de Co
Georgia Chenevix-TrenchUniversity of Cambridge, MRC Institute of Genetics and Molecular Medicine (A. Campbell, University of Edinburgh, University of Edinburgh Medical School (A. Campbell, Health Services Research, University of Manchester, the NIHR Manchester Biomedical Research Unit (E.F.H.) and the Nightingale Breast Screening Centre, Wythenshawe Hospital (E.F.H., St. Mary's Hospital, Manchester University NHS Foundation Trust (W.G.N., the School of Cancer and Pharmaceutical Sciences, Comprehensive Cancer Centre, King's College London, the Institute of Cancer and Genomic Sciences, University of Birmingham, and the Wellcome Trust Centre for Human Genetics and Oxford NIHR Biomedical Research Centre, University of Oxford, Spanish National Cancer Research Center, Hospital Universitario La Paz (M.P.Z.), Hospital Clinico San Carlos, Instituto de Investigacion Sanitaria del Hospital Clinico San Carlos (M. de la Hoya), Galician Foundation of Genomic Medicine, Instituto de Investigacion Sanitaria de Santiago de Co
Javier Ben??tezUniversity of Cambridge, MRC Institute of Genetics and Molecular Medicine (A. Campbell, University of Edinburgh, University of Edinburgh Medical School (A. Campbell, Health Services Research, University of Manchester, the NIHR Manchester Biomedical Research Unit (E.F.H.) and the Nightingale Breast Screening Centre, Wythenshawe Hospital (E.F.H., St. Mary's Hospital, Manchester University NHS Foundation Trust (W.G.N., the School of Cancer and Pharmaceutical Sciences, Comprehensive Cancer Centre, King's College London, the Institute of Cancer and Genomic Sciences, University of Birmingham, and the Wellcome Trust Centre for Human Genetics and Oxford NIHR Biomedical Research Centre, University of Oxford, Spanish National Cancer Research Center, Hospital Universitario La Paz (M.P.Z.), Hospital Clinico San Carlos, Instituto de Investigacion Sanitaria del Hospital Clinico San Carlos (M. de la Hoya), Galician Foundation of Genomic Medicine, Instituto de Investigacion Sanitaria de Santiago de Co
Alison M DunningUniversity of Cambridge, MRC Institute of Genetics and Molecular Medicine (A. Campbell, University of Edinburgh, University of Edinburgh Medical School (A. Campbell, Health Services Research, University of Manchester, the NIHR Manchester Biomedical Research Unit (E.F.H.) and the Nightingale Breast Screening Centre, Wythenshawe Hospital (E.F.H., St. Mary's Hospital, Manchester University NHS Foundation Trust (W.G.N., the School of Cancer and Pharmaceutical Sciences, Comprehensive Cancer Centre, King's College London, the Institute of Cancer and Genomic Sciences, University of Birmingham, and the Wellcome Trust Centre for Human Genetics and Oxford NIHR Biomedical Research Centre, University of Oxford, Spanish National Cancer Research Center, Hospital Universitario La Paz (M.P.Z.), Hospital Clinico San Carlos, Instituto de Investigacion Sanitaria del Hospital Clinico San Carlos (M. de la Hoya), Galician Foundation of Genomic Medicine, Instituto de Investigacion Sanitaria de Santiago de Co
Douglas F EastonUniversity of Cambridge, MRC Institute of Genetics and Molecular Medicine (A. Campbell, University of Edinburgh, University of Edinburgh Medical School (A. Campbell, Health Services Research, University of Manchester, the NIHR Manchester Biomedical Research Unit (E.F.H.) and the Nightingale Breast Screening Centre, Wythenshawe Hospital (E.F.H., St. Mary's Hospital, Manchester University NHS Foundation Trust (W.G.N., the School of Cancer and Pharmaceutical Sciences, Comprehensive Cancer Centre, King's College London, the Institute of Cancer and Genomic Sciences, University of Birmingham, and the Wellcome Trust Centre for Human Genetics and Oxford NIHR Biomedical Research Centre, University of Oxford, Spanish National Cancer Research Center, Hospital Universitario La Paz (M.P.Z.), Hospital Clinico San Carlos, Instituto de Investigacion Sanitaria del Hospital Clinico San Carlos (M. de la Hoya), Galician Foundation of Genomic Medicine, Instituto de Investigacion Sanitaria de Santiago de Co
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