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Paper Details

Enhancer Reprogramming within Pre-existing Topologically Associated Domains Promotes TGF-β-Induced EMT and Cancer Metastasis.
Mol Ther
19
2020
Cancer, Enhancers, FOXA2, H3K27ac, HDAC1, SMAD2/3, TADs, TEAD4, TGF, TGF-, TGF--, Topologically Associated Domains, Transcription growth factor, cancer, enhancers, epithelial cells, epithelial-specific enhancer, genome, histone, histone H3 lysine 27, histone H3 lysine 27 acetylation (H3K27ac)-marked enhancers, lysine, mesenchymal enhancer, topologically associated domains, tumor
A549 Cells, Animals, Carcinogenesis, Cellular Reprogramming, DNA-Binding Proteins, Enhancer Elements, Genetic, Epithelial-Mesenchymal Transition, HEK293 Cells, Hepatocyte Nuclear Factor 3-beta, Hepatocytes, Histone Deacetylase 1, Histones, Humans, Mice, Muscle Proteins, Neoplasm Metastasis, Signal Transduction, Smad2 Protein, Smad3 Protein, TEA Domain Transcription Factors, Transcription Factors, Transcriptional Activation, Transforming Growth Factor beta
Author NameAffiliation
Yunbo QiaoGuangzhou University
Zejian WangShanghaiTech University, China University of Chinese Academy of Sciences
Fangzhi TaniHuman Institute, ShanghaiTech University
Jun ChenState Key Laboratory of Medicinal Chemical Biology and College of Life Sciences, Nankai University
Jianxiang LinGuangzhou University
Jie YangUniversity of Chinese Academy of Sciences
Hui LiUniversity of Chinese Academy of Sciences
Xiongjun WangGuangzhou University
Andrej Sali (CM4AI)Department of Pharmaceutical Chemistry, and California Institute for Quantitative Biosciences, University of California san francisco
Andrej Sali (CM4AI)Department of Pharmaceutical Chemistry, and California Institute for Quantitative Biosciences, University of California san francisco
Liye ZhangShanghaiTech University
Guisheng ZhongShanghaiTech University, China iHuman Institute
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