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Paper Title
HIV-1 Tat and host AFF4 recruit two transcription elongation factors into a bifunctional complex for coordinated activation of HIV-1 transcription.
PubMed
Paper Journal Title
Mol Cell
Paper Citation Count
317
Paper Publication Year
2010
Bio Mention
AF9, AFF4, ELL2, ENL, HIV, HIV-1, HIV-1 Tat, P-TEFb, P-TEFb kinase, RNA polymerase II, Tat, elongation factor ELL2, elongation factors, host AFF4, human, transcription elongation factors, viral promoter
Mesh Descriptor
Binding Sites, Cell Line, Cyclin-Dependent Kinase 9, HIV-1, Host-Pathogen Interactions, Humans, Multiprotein Complexes, Nuclear Proteins, Positive Transcriptional Elongation Factor B, Promoter Regions, Genetic, Proteasome Endopeptidase Complex, Proteasome Inhibitors, RNA Interference, RNA, Viral, Repressor Proteins, Transcriptional Activation, Transcriptional Elongation Factors, Transfection, tat Gene Products, Human Immunodeficiency Virus
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Affiliation
Nanhai He
University of California berkeley
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