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Paper Details

Multimodal pooled Perturb-CITE-seq screens in patient models define mechanisms of cancer immune evasion.
Nat Genet
91
2021
), CD58, CD58 protein, CRISPR, Cas9, ICI, ICR, IFN, JAK, MHC, RNA, STAT, autologous tumor-infiltrating lymphocyte (TIL) co-cultures, cancer, cancer cell, clustered regularly interspaced short palindromic repeat, co-culture models, interferon, major histocompatibility complex, melanoma, melanoma cells, patient, patient-derived melanoma cells, patients, tumors
Author NameAffiliation
Michael S CuocoBroad Institute of MIT and Harvard
Orit Rozenblatt-RosenBroad Institute of MIT and Harvard
Orit Rozenblatt-Rosen
Dirk SchadendorfUniversity Hospital Essen and German Cancer Consortium
Aviv RegevBroad Institute of MIT and Harvard
Aviv RegevMassachusetts Institute of Technology
Aviv RegevHoward Hughes Medical Institute
Aviv Regev
Aviv RegevBroad Institute of MIT and Harvard
Aviv RegevMassachusetts Institute of Technology
Aviv RegevHoward Hughes Medical Institute
Aviv Regev
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