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Paper Details

A Point Mutation R122C in RUNX3 Promotes the Expansion of Isthmus Stem Cells and Inhibits Their Differentiation in the Stomach.
Cell Mol Gastroenterol Hepatol
8
2022
Isthmus Stem Cells, MYC target gene, MYC target gene signature, R122C, RNA, RUNX, RUNX transcription factors, RUNX3, RUNX3 mutant protein, corpus epithelial cells, epithelial cells, gastric cancer, gastric corpus isthmus and nonisthmus epithelial cells, human, isthmus stem/progenitor cells, metaplasia, mice, mucous neck cell hyperplasia, neoplasia, organoid, pit, pit, parietal, and chief cell populations, proliferating isthmus stem/progenitor cells, spasmolytic polypeptide-expressing metaplasia, stem cell, wild-type
Author NameAffiliation
Henry YangCancer Science Institute of Singapore, National University of Singapore
Henry YangCancer Science Institute of Singapore, National University of Singapore
Yoshiaki ItoCancer Science Institute of Singapore, National University of Singapore
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