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Paper Details

The Akt/mTOR and MNK/eIF4E pathways rewire the prostate cancer translatome to secrete HGF, SPP1 and BGN and recruit suppressive myeloid cells.
Nat Cancer
4
2023
AKT, Akt, BGN, Bgn, Cancer, HGF, Hgf, MDSC, MDSCs, MNK, MNK1/2, Pdcd4, SPP1, Spp1, eFT508, eIF4E, ipatasertib, mRNAs, mTOR, myeloid cells, myeloid-derived suppressor cells, prostate, prostate cancer, prostate cancers, prostate tumor, tumor
Author NameAffiliation
Toma TebaldiYale Cancer Center and Department of Internal Medicine, Yale University School of Medicine
Adam SharpInstitute of Cancer Research and Royal Marsden NHS Foundation Trust
Wei YuanInstitute of Cancer Research and Royal Marsden NHS Foundation Trust
Holger MochUniversity Hospital Zurich (USZ)
Holger MochUniversity Hospital Zurich (USZ)
Johann S de BonoInstitute of Cancer Research and Royal Marsden NHS Foundation Trust
Johann S de BonoThe Royal Marsden Hospital
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